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    Respiratory Treatment and Prevention [Electronic resource] / ed. Pokorski, Mieczyslaw. - 1st ed. 2017. - [S. l. : s. n.]. - VIII, 88 p. 12 illus., 1 illus. in color. - ISBN 9783319444888
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Рубрики: Respiratory organs—Diseases.
   Bacteriology.
   Pneumology/Respiratory System.
   Bacteriology.
Анотація: The goal of this book is to further insight into the challenges related to respiratory health. Medical experts present their lines of scientific investigations on how to contain the disease, care for patients, and use preventive measures, with a focus on pulmonary-related disorders. Progress in the diagnostics and treatment of major infectious diseases affecting humanity such as tuberculosis, malaria, fungal and viral contagions is tackled. Other chapters provide some background information on the mechanisms and prevention of non-communicable diseases. New aspects of the etiology of sarcoidosis, air pollution-related lung cancer, and sleep disordered breathing are presented. Preventive measures of health in general and respiratory health in particular cannot do without a reminder of cigarette smoke avoidance and the respiratory aftermath of the smoking habit. The book presents scientific evidence-based practice knowledge. It is intended for healthcare professionals, specifically pulmonary specialists, primary care physicians, and all scientifically-minded individuals involved in the care of patients.
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    Clinical Management of Pulmonary Disorders and Diseases [Electronic resource] / ed. Pokorski, Mieczyslaw. - 1st ed. 2017. - [S. l. : s. n.]. - VIII, 86 p. - ISBN 9783319695457
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Рубрики: Respiratory organs—Diseases.
   Neurosciences.
   Cell biology.
   Pneumology/Respiratory System.
   Neurosciences.
   Cell Biology.
Анотація: The book endeavors to provide a stimulating and thought provoking scientific content to share and exchange new clinical studies and advancements in dealing with pulmonary diseases. The topics vary from clinical to translational research in respiratory diseases such as lung cancer, obstructive sleep apnea, chronic obstructive pulmonary disease, bacterial and fungal infections, lung lesions during febrile maladies, and others. An attempt has been made to show the intertwined relationship between the pulmonary system and other body systems such as kidney, cardiac, or hormonal functions. The ensuing interlocked morbidities, often exacerbating one another, require the coordination of various medical specialties to optimize the diagnostic and therapeutic processes. The knowledge sharing through publications of research and clinical experiences is indispensable to accelerate the innovation spectrum and to continue working on the therapeutic and preventive strategies in chronic pulmonary diseases. The book is addressed to pulmonologists, chest physicians, researchers, and healthcare professionals engaged in patient care.
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    Pulmonary Vasculature Redox Signaling in Health and Disease [Electronic resource] / ed. Wang, Yong-Xiao. - 1st ed. 2017. - [S. l. : s. n.]. - XXI, 422 p. 57 illus., 41 illus. in color. - ISBN 9783319632452
    Зміст:

Chapter1. Adventitial Fibroblast Nox4 Expression and ROS Signaling in Pulmonary Arterial Hypertension -- Chapter2. Role of Transcription Factors in Pulmonary Artery Smooth Muscle Cells: An important Link to Hypoxic Pulmonary Hypertension -- Chapter3. Molecular Basis of Nitrative Stress in the Pathogenesis of Pulmonary Hypertension -- Chapter4. Pentose Shunt, Glucose-6-phosphate dehydrogenase and NADPH redox, and Stem cells in Pulmonary Hypertension -- Chapter5. Redox regulation of the superoxide dismutases SOD3 and SOD2 in the pulmonary circulation. – Chapter6. A Brief Overview of Nitric Oxide and Reactive Oxygen Species Signaling In Hypoxia-Induced Pulmonary Hypertension -- Chapter7. Altered redox balance in the development of chronic hypoxia- induced pulmonary hypertension -- Chapter8. ROS signaling in the pathogenesis of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) -- Chapter9. Redox-dependent calpain signaling in airway and pulmonary vascular and remodeling in COPD -- Chapter10. Natural antioxidants as potential therapy, and a promising role for melatonin against pulmonary hypertension -- Chapter11. Effects of Hyperoxia on the Developing Airway and Pulmonary Vasculature -- Chapter12. Lung ischemia/reperfusion injury – the role of reactive oxygen species -- Chapter13. Redox Mechanisms Influencing cGMP Signaling in Pulmonary Vascular Physiology and Pathophysiology -- Chapter14. Metabolic Reprogramming and Redox Signaling in Pulmonary Hypertension -- Chapter15. Hydrogen sulfide as an O2 sensor: a critical analysis -- Chapter16. Redox Signaling and Persistent Pulmonary Hypertension of the Newborn -- Chapter17. Crosstalk between mitochondrial reactive oxygen species and sarcoplasmic reticulum calcium in pulmonary arterial smooth muscle cells -- Chapter18. Endothelial Cell Reactive Oxygen Species and Ca2+ Signaling in Pulmonary Hypertension -- Chapter19. Redox signaling in the right ventricle -- Chapter20. Hypoxia and Local Inflammation in Pulmonary Artery Structure and Function -- Chapter21. From physiological redox signalling to oxidant stress -- Chapter22. Emerging Role of MicroRNAs and Long Noncoding RNAs in Healthy and Diseased Lung -- Chapter23. Techniques for Detecting Reactive Oxygen Species in Pulmonary Vasculature Redox Signaling -- Chapter24. Mitochondrial and metabolic drivers of pulmonary vascular endothelial dysfunction in pulmonary hypertension -- Chapter25. Subcellular Redox Signaling -- Chapter26. Reactive oxygen species in COPD-related vascular remodeling.

Рубрики: Human physiology.
   Respiratory organs—Diseases.
   Cell physiology.
   Human Physiology.
   Pneumology/Respiratory System.
   Cell Physiology.
Анотація: The main goal of this book is to form a high-quality platform in which well-known and emerging pioneering basic, translational and clinical scientists can present their latest, exciting findings in the studies of redox signaling in the pulmonary vasculature. Content from outstanding investigators with unique expertise and skills of molecular and cell biology, biochemistry, physiology, pharmacology, biophysics, biotechnology and medicine will update our current out-of-date concepts with new knowledge. Rapidly increasing scientific studies have gathered a large volume of novel and important information on redox signaling in healthy and diseased pulmonary vasculature. This volume covers the need for a cohesive book to display state-of-the-art advances in the field.    The second major aim of this book is to help direct future research. Redox signaling is a major molecular process involved in almost every physiologic cellular response in the pulmonary vasculature including energy metabolism, host defense, gene expression, contraction, proliferation, and migration. Aberrancy in this important signaling pathway leads to a critical role in the development of nearly all pulmonary diseases, such as pulmonary hypertension, cor pulmonale, pulmonary edema, and vasculitis, among others.  .
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    Sepsis [Electronic resource] : definitions, Pathophysiology and the Challenge of Bedside Management / / ed.: Ward, Nicholas S., Levy, Mitchell M. - 1st ed. 2017. - [S. l. : s. n.]. - XI, 271 p. 16 illus., 8 illus. in color. - ISBN 9783319484709
    Зміст:

Рубрики: Respiratory organs—Diseases.
   Critical care medicine.
   Pneumology/Respiratory System.
   Intensive / Critical Care Medicine.
Анотація: This book is designed to provide a comprehensive and state-of-the-art resource for clinicians who care for patients with sepsis and research scientist alike, . Patients with severe sepsis requiring ICU admission have very high rates of ICU and overall hospital mortality, with estimates ranging from 18 to 50%. Risk factors for death from sepsis include underlying illness, increased age, and multi-system organ failure. This is compounded by the significant variation in the management of early severe sepsis. Care of these patients and clinical conditions can be quite complex, and materials are collected from the most current, evidence-based resources. Book sections have been structured to review the overall definitions and epidemiology of sepsis as well as current insights into the pathophysiology of sepsis. This review summarizes the evidence for the international consensus guidelines for the identification and management of sepsis. The latter part of this book reviews emerging concepts and approaches in the diagnosis and management of sepsis that may significantly reduce mortality in the future. Sepsis: Pathophysiology, Definitions and the Challenge of Bedside Management represents a collaboration between authors drawn from a variety of disciplines and contributions from basic scientists and highly recognized clinical opinion leaders with expertise in clinical trials.
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Ward, Nicholas S. \ed.\; Levy, Mitchell M. \ed.\
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    Treatment of Cystic Fibrosis and Other Rare Lung Diseases [Electronic resource] / ed.: Azuma, Arata., Schechter, Michael S. - 1st ed. 2017. - [S. l. : s. n.]. - VIII, 263 p. 33 illus., 14 illus. in color. - ISBN 9783034809771
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Рубрики: Pharmacology.
   Respiratory organs—Diseases.
   Internal medicine.
   Immunology.
   Pharmacology/Toxicology.
   Pneumology/Respiratory System.
   Internal Medicine.
   Immunology.
Анотація: This volume describes the pathogenesis and pathophysiology of several pulmonary diseases as well as their treatment. It also discusses the underlying genetic and molecular biological basis, which opens the way for new treatments for these conditions. It focuses on the treatment of cystic fibrosis including CFTR (cystic fibrosis transmembrane-conductance regulator) modulator therapies, drug therapies that augment airway surface liquid as well as anti-inflammatory and anti-infective therapies. Further topics include long-term, low-dose macrolide therapy for diffuse panbronchiolitis; novel agents for previously untreatable idiopathic pulmonary fibrosis; possible new treatments for pulmonary alveolar proteinosis (PAP); and multiple novel therapeutic targets for treating lymphangiomyomatosis. Research into these conditions has led to major advances in our understanding of the underlying genetic and molecular basis of this disease, and to dramatic improvements in survival and quality of life for affected individuals.
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Azuma, Arata. \ed.\; Schechter, Michael S. \ed.\
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    Pharmacology and Therapeutics of Asthma and COPD [Electronic resource] / ed.: Page, Clive P., Barnes, Peter J. - 1st ed. 2017. - [S. l. : s. n.]. - X, 285 p. - ISBN 9783319521756
    Зміст:

Рубрики: Pharmacology.
   Respiratory organs—Diseases.
   Dermatology.
   Pharmacology/Toxicology.
   Pneumology/Respiratory System.
   Dermatology.
Анотація: The present volume is supposed to be a major reference resource for chest physicians and those involved in the development of novel pharmaceutical entities for these diseases. Internationally recognized authorities review the most important new information on the advances in our understanding of the pathogenesis and treatment of these diseases, including the substantial advances in the topical delivery of inhaled medicines. Each chapter is extensively referenced, generously illustrated with clear diagrams and photographs, and represents a state-of-the-art review of this important area of respiratory medicine.
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Page, Clive P. \ed.\; Barnes, Peter J. \ed.\
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    Pathobiology of Pulmonary Disorders [Electronic resource] / ed. Pokorski, Mieczyslaw. - 1st ed. 2017. - [S. l. : s. n.]. - VIII, 76 p. - ISBN 9783319492957
    Зміст:

Рубрики: Respiratory organs—Diseases.
   Microbiology.
   Pneumology/Respiratory System.
   Microbiology.
Анотація: Pulmonary disorders significantly contribute to the current level of disease burden. Effective disease management is essential for improving clinical outcomes and quality of life. This book highlights the issues involved with diagnosing and managing various pulmonary conditions such as chronic obstructive pulmonary disorders, respiratory tract infections, including those developing as a sequel of antibiotic treatment, and others. Investigations on novel diagnostic procedures and potential biomarkers of diseases are discussed, along with disease presentations and management. Preventive measures related to lifestyle and air quality, with the implications on patients care, are tackled as well. Progress in clinical savvy is inseparably linked with getting an insight into the pathogenesis of a condition. This book presents views and information on the research developments in the rapidly changing field of pneumology. Target readership: clinicians and researchers, family practitioners, and trainees.
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    Influenza and Respiratory Care [Electronic resource] / ed. Pokorski, Mieczyslaw. - 1st ed. 2017. - [S. l. : s. n.]. - VIII, 95 p. - ISBN 9783319517124
    Зміст:

Рубрики: Respiratory organs—Diseases.
   Virology.
   Neurobiology.
   Pneumology/Respiratory System.
   Virology.
   Neurobiology.
Анотація: Respiratory infections constitute a major public health concern. The goal of this book is to share knowledge on the best advances in influenza and influenza-like viral infections, and new molecular-based diagnostic methods that discern the antigenic shift enabling viruses to constantly evolve and elude the host immune response. Co-infections, co-morbidities, persistently meager anti-flu vaccination coverage, and infection complications are dealt with. The chapters also further insight into such topics as the effects of sex hormones, and socioeconomic and anthropometric measures on respiratory and immune functions underlying the severity of asthma and respiratory allergy. Psychological functioning in respiratory disorders, taking into account quality of life, illness acceptance, and depressive symptoms is also reviewed as it is all too often underestimated by healthcare providers. The book is intended for clinicians, researchers, students, and all other actors in health-related issues.
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    Diagnosis and Treatment of Pulmonary Hypertension [Electronic resource] : from Bench to Bedside / / ed. Fukumoto, Yoshihiro. - 1st ed. 2017. - [S. l. : s. n.]. - VIII, 236 p. 70 illus., 45 illus. in color. - ISBN 9789812878403
    Зміст:

Рубрики: Cardiology.
   Respiratory organs—Diseases.
   Cardiac surgery.
   Cardiology.
   Pneumology/Respiratory System.
   Cardiac Surgery.
Анотація: This book focuses on pulmonary arterial hypertension (PAH, Group 1) and chronic thromboembolic pulmonary hypertension (CTEPH, Group 4) among the various groups of pulmonary hypertension (PH) whose classification was updated into five major categories at the 5th World Symposium held in Nice, France, in 2013. Readers will find recent progress, methods, and up-to-date information on PH mechanisms, diagnostic images, and treatment in the management of PH. This volume, with contributions by leading researchers worldwide in the field , consists of five parts, starting with the fundamentals of PH, then pathophysiology and genetics, treatment, and right ventricular function.
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10.

    Molecular Targeted Therapy of Lung Cancer [Electronic resource] / ed. Takiguchi, Yuichi. - 1st ed. 2017. - [S. l. : s. n.]. - X, 327 p. 54 illus., 48 illus. in color. - ISBN 9789811020025
    Зміст:

Рубрики: Respiratory organs—Diseases.
   Oncology  .
   Molecular biology.
   Pneumology/Respiratory System.
   Oncology.
   Molecular Medicine.
Анотація: This book discusses the latest molecular targeted therapy of lung cancer including its evaluation and future directions. It clearly illustrates the initial dramatic effectiveness of molecular targeted therapy, recurrence of the disease, overcoming the wide variety of resistance mechanisms using new-generation molecular targeted agents and potential novel approaches. It also outlines the increasing necessity for new diagnostic technology and strategies for managing different adverse effects and novel methods for evaluating effectiveness and safety. Edited and authored by opinion leaders, Molecular Targeted Therapy of Lung Cancer provides a comprehensive overview of the disease and its treatments. It is a valuable resource for graduate students, post-doctoral fellows and faculty staff, as well as researchers involved in clinical and translational research on lung cancer, helping promote new ideas for further advances.
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11.

    Respiratory Endoscopy [Electronic resource] / ed. Izumo, Takehiro. [et al.]. - 1st ed. 2017. - [S. l. : s. n.]. - IX, 259 p. 225 illus., 148 illus. in color. - ISBN 9789812879165
    Зміст:

Part I Edition for Radiological Technicians -- 1. The Role of X-ray Fluoroscopy in Bronchoscopy -- 2. Development of X-ray Fluoroscopy Devices -- 3. Characteristics of X-ray Fluoroscopy -- 4. Image Processing of X-ray Fluoroscopy and New Digital Tomography -- 5. Quality Control in X-ray Fluoroscopy and Digital Tomography -- 6. Computed Tomography Imaging to Bronchoscopic Navigation -- Part II Edition for Doctors -- 7. Fluorographic and Radiographic Conditions in Bronchoscopy Using X-ray Fluoroscopy -- 8. Identification of the Involved Bronchus to Peripheral Pulmonary Lesions on Computed Tomography -- 9. Anesthesia for Bronchoscopy -- 10. Processing Samples -- 11. Rapid On-site Cytology Evaluation -- 12. Type and Selection of Flexible Bronchoscope -- 13. Latest in Bronchoscopy (Hi-Vision Scope with Rotation Function) -- 14. Basic Flexible Bronchoscopy -- 15. Tomography-Guided Transbronchial Biopsy for Peripheral Pulmonary Lesions -- 16. Radial Endobronchial Ultrasound Findings -- 17. Radial EBUS Findings for Ground Glass Opacity: Comparison of Radiologic and Pathologic Findings -- 18. Endobronchial Ultrasound with a Guide Sheath for Peripheral Pulmonary Lesions -- 19. Transbronchial Needle Aspiration Through a Guide Sheath for Peripheral Pulmonary Lesions -- 20. Virtual Bronchoscopic Navigation for Peripheral Pulmonary Lesions -- 21. Virtual Bronchoscopic Simulation by CT Workstation -- 22. The Dose and Risk Factors for Radiation Exposure from X-ray Fluoroscopy during EBUS-GS for Peripheral Pulmonary Lesions -- 23. Endobronchial Ultrasound-guided Transbronchial Needle Aspiration -- 24. Endobronchial Ultrasound Elastography -- 25. Flex-rigid Pleuroscopy under Local Anesthesia -- 26. Stent Placement Under X-ray Fluoroscopy -- 27. Therapeutic Bronchoscopy for Central Airway Obstruction (Balloon, Argon Plasma Coagulation, High Frequency) -- 28. Endoscopic Bronchial Occlusion With Silicone Spigots -- 29. Photodynamic Therapy for Lung Cancer -- Part III Edition for Nurses -- 30. Actual Nursing in Respiratory Endoscopy.

Рубрики: Respiratory organs—Diseases.
   Oncology  .
   Radiology.
   Nursing.
   Pneumology/Respiratory System.
   Oncology.
   Diagnostic Radiology.
   Nursing.
Анотація: This book provides a detailed overview of the latest innovations in respiratory endoscopy, from both diagnostic and therapeutic perspectives; each chapter focuses on one disease and the techniques for early diagnosis as well as treatment. It comprehensively covers treatment and procedures, including simultaneous X-ray fluoroscopy and its use during bronchoscopic procedures. This fast-developing technology is essential for the medical management of non-malignant and malignant diseases of the chest, especially lung cancer. Respiratory Endoscopy describes the cooperation between all the members of the healthcare team, and as such is a valuable resource not only for medical staff, but also for radiological technicians and nursing staff who contribute significantly in the care of the patients undergoing these invasive procedures. By promoting teamwork and providing practical know-how, it will improve the success and safety of respiratory endoscopy procedures.
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Izumo, Takehiro. \ed.\; Sasada, Shinji. \ed.\; Aso, Tomohiko. \ed.\; Nasu, Kazuko. \ed.\; Arai, Yasuaki. \ed.\
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12.

    Manual of Neonatal Respiratory Care [Electronic resource] / ed.: Donn, Steven M., Sinha, Sunil K. - 4th ed. 2017. - [S. l. : s. n.]. - XXXI, 820 p. 215 illus., 86 illus. in color. - ISBN 9783319398396
    Зміст:

Development of the Respiratory System -- Malformations, Deformations, and Disorders of the Neonatal Airway -- Developmental Lung Anomalies -- Spontaneous Breathing -- Pulmonary Gas Exchange -- Oxygen Therapy -- Oxygen Toxicity -- Pulmonary Mechanics and Energetics -- Basic Principles of Mechanical Ventilation -- Classification of Mechanical Ventilation Devices -- Ventilator Parameters -- Respiratory Gas Conditioning and Humidification -- Cardio-Respiratory Examination -- Neonatal Resuscitation -- Laryngoscopy and Endotracheal Intubation -- Vascular Access -- Tracheostomy -- Continuous Monitoring Techniques -- Clinical Controversies: Pulse Oximetry -- Interpretation of Blood Gases -- Volumetric Capnography -- Neonatal Pulmonary Graphics -- Diagnostic Imaging -- Transillumination -- Echocardiography -- Bronchoscopy -- Nasal Interfaces for Non-Invasive Ventilation -- Humidified High-Flow Nasal Cannula Therapy -- Continuous Distending Pressure -- Sustained Inflation -- Noninvasive Ventilation: An Overview -- Nasal Intermittent Positive Pressure Ventilation -- Precision Flow Vapotherm -- Intermittent Mandatory Ventilation -- Synchronized Intermittent Mandatory Ventilaton -- Assist/Control Ventilation -- Pressure Support Ventilation -- Volume-Targeted Ventilation -- Volume Guarantee Ventilation -- Pressure Control Ventilation -- High-Frequency Ventilation: General Concepts -- High-Frequency Jet Ventilation -- High-Frequency Oscillatory Ventilation -- Ventilator Mode Classification -- VIP BIRD Gold Ventilator -- AVEA Ventilator -- Twinstream Ventilator -- Puritan Bennett 840 and Puritan Bennett 980 Ventilators -- Draeger VN500 -- Servo-i Ventilator and NAVA -- SLE 5000 and SLE 4000 Infant Ventilators -- STEPHANIE and SOPHIE Ventilators -- Leoni Plus Ventilator -- Bunnell Life Pulse High-Frequency Jet Ventilator -- High Frequency Oscillatory Ventilators -- Hemodynamic Support -- Nutritional Support in Respiratory Failure -- Surfactant Administration -- Pharmacologic Agents -- Automatic Control of Oxygen Delivery -- Aerosolization and Nebulization -- Sedation and Analgesia -- Inhaled Nitric Oxide Therapy -- Extracorporeal Membrane Oxygenation -- Liquid Ventilation for Neonatal Respiratory Failure -- Mechanisms of Respiratory Failure -- Tissue Hypoxia -- Indications for Mechanical Ventilation -- Respiratory Distress Syndrome -- Pneumonia -- Meconium Aspiration Syndrome -- Persistent Pulmonary Hypertension of the Newborn -- Congenital Diaphragmatic Hernia -- Pulmonary Hypoplasia/Agenesis -- Chylothorax -- Apnea, Bradycardia, and Desaturation -- Optimizing Lung Volume -- Weaning and Extubation -- Etiology and Pathogenesis -- Bronchopulmonary Dysplasia: Clinical Management -- Long-Term Outcome of Newborns with Bronchopulmonary Dysplasia -- Thoracic Air Leaks -- Patent Ductus Arteriosus -- Neonatal Pulmonary Hemorrhage -- Retinopathy of Prematurity -- Neurologic Complications of Mechanical Ventilation -- Nursing Care of the Ventilated Infant -- Transport of Ventilated Babies -- Role of the Respiratory Therapist in the NICU -- Long Term Ventilator Dependency in Infants without Lung Disease -- Chronic Home Mechanical Ventilation -- Discharge Planning and Follow-Up of the NICU Graduate -- Initiation of Life Support at the Border of Viability -- Withdrawal of Ventilatory Support -- Medical Liability, Documentation, and Risk Management -- Interpreting Medical Literature -- Data Collection and Assessment of Respiratory Outcomes -- Practical Quality Improvement in the NICU -- Contemporary Classics in Neonatal Respiratory Care -- Ventilatory Cases.

Рубрики: Pediatrics.
   Respiratory organs—Diseases.
   Critical care medicine.
   Anesthesiology.
   Emergency medicine.
   Pediatrics.
   Pneumology/Respiratory System.
   Intensive / Critical Care Medicine.
   Anesthesiology.
   Emergency Medicine.
Анотація: The latest edition of this popular book covers the “how-to” of respiratory care of newborns. Chapters from the previous edition have been updated to reflect advances in both equipment and practice, while newer chapters reflect the evolving worldwide approaches to neonatal respiratory failure, such as sustained inflation, optimization of lung volume, and the use of volumetric capnography, aerosol therapy, and management of chylothorax. New additions to the book also include chapters on assessment of large data bases, implementation of quality improvement programs in neonatal respiratory care, chronic ventilation of the baby with non-respiratory failure. The text also features case studies for self-review and is illustrated with high quality radiographic images, figures, tables, and algorithms. Written and edited by international experts, the Manual of Neonatal Respiratory Care, Fourth Edition is a thorough update and remains a convenient source of practical information on respiratory physiology, exam techniques, tips for performing procedures, radiography, ventilation, pain management, transport, and discharge planning.
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Donn, Steven M. \ed.\; Sinha, Sunil K. \ed.\
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13.

    Scleroderma [Electronic resource] : from Pathogenesis to Comprehensive Management / / ed. Varga, John. [et al.]. - 2nd ed. 2017. - [S. l. : s. n.]. - XXXV, 743 p. 191 illus., 174 illus. in color. - ISBN 9783319314075
    Зміст:

Section I. Introduction -- Historical Perspective of Scleroderma -- Section II. Epidemiology, Genetics and Classification -- Epidemiology, Environmental and Infectious Risk Factors -- Genetic Factors -- Disease Subsets in Clinical Practice -- Evolving Concepts of Diagnosis and Classification -- Overlap Syndromes -- Juvenile Localized and Systemic Scleroderma -- Morphea (Localized Scleroderma) -- Scleroderma Mimics -- Systems Biology Approaches to Understanding the Pathogenesis of Systemic Sclerosis -- Section III: The Biological Basis of Systemic Sclerosis -- Introduction: The Etiopathogenesis of Systemic Sclerosis: An Integrated Overview -- Pathology of Systemic Sclerosis -- Inflammation and Immunity -- Autoantibodies as Markers and Possible Mediators of Scleroderma Pathogenesis -- The Clinical Aspects of Autoantibodies -- Mechanisms of Vascular Disease -- Biomarkers in Systemic Sclerosis -- Pathophysiology of Fibrosis in Systemic Sclerosis -- Overview of Animal Models -- Section IV. Cardiovascular Manifestations and Management -- Raynaud’s Phenomenon, Digital Ulcers, and Nailfold Capillaroscopy -- Renal Crisis and Other Renal Manifestations of Scleroderma -- Cardiac Involvement -- Section V. Pulmonary Manifestations and Management -- Overview of Lung Involvement: Diagnosis, Differential Diagnosis, and Monitoring -- Clinical Assessment of Lung Disease -- Treatment of Interstitial Lung Disease -- Pathogenesis of Pulmonary Arterial Hypertension -- Clinical Assessment of Pulmonary Hypertension -- The Management of Pulmonary Arterial Hypertension in the Setting of Systemic Sclerosis -- Section VI. Gastrointestinal Manifestations and Management -- Overview of Gastrointestinal Tract Involvement -- Upper Gastrointestinal Tract: Manifestations of Systemic Sclerosis -- Small and Large Intestinal Involvement and Nutritional Issues -- Section VII. Skin, Musculoskeletal and Other Complications -- Calcinosis -- Evaluation and Management of Skin Disease -- Assessment and Management of Progressive Skin Involvement in Diffuse Scleroderma -- Skeletal Muscle Involvement -- Tendons, Joints, and Bone -- Cancer in Systemic Sclerosis -- Overlooked Manifestations -- Pregnancy -- Section VIII: Management and Outcome Assessment -- Introduction to Section VIII: Management and Outcome Assessment -- Immunomodulatory, Immunoablative, and Biologic Therapies -- Investigative Approaches to Drug Therapy -- Drug Development and Regulatory Considerations for SSc Therapies -- Physical and Occupational Therapy -- Psychosocial Issues and Care for Patients with Systemic Sclerosis -- Clinical Trial Design in Systemic Sclerosis -- Measuring Disease Activity and Outcomes in Clinical Trials -- Innovative Approaches to Clinical Trials in Systemic Sclerosis -- Molecular Stratification by Gene Expression as a Paradigm for Precision Medicine in Systemic Sclerosis -- Section IX. Case Studies: Approach to Complex Clinical Problems -- Managing the Ischemic Finger in Scleroderma -- Scleroderma Renal Crisis -- Rapid Diffuse Skin Disease with Progressive Joint Contractures -- Management of the Scleroderma Patient with Pulmonary Arterial Hypertension Failing Initial Therapy -- Pseudo-obstruction with Malabsorption and Malnutrition -- Progressive Interstitial Lung Disease Non-Response to Cyclophosphamide -- Coping with the Disfigurement of Scleroderma: Facial, Skin, and Hand Changes -- Managing Complicated Digital Ulcers .

Рубрики: Rheumatology.
   Respiratory organs—Diseases.
   Dermatology.
   Rheumatology.
   Pneumology/Respiratory System.
   Dermatology.
Анотація: Comprised of the authoritative work of international experts, this fully-updated second edition of Scleroderma builds upon the well-regarded approach in the first edition to provide integrated, concise, and up-to-date synthesis of current concepts of pathogenesis and modern approaches to management of systemic sclerosis (scleroderma). With a multidisciplinary approach to comprehensive care, this book is easily accessible for health care professionals in many fields. The new edition includes extensive updated material based on major developments in the field, with new chapters on personalized medicine, cancer complications, global perspectives on scleroderma, and more. It presents a succinct and thoughtful synthesis of current pathomechanistic concepts, providing a valuable reference tool for basic and translational investigators working in the field. Scleroderma: From Pathogenesis to Comprehensive Management serves as an essential, all-inclusive resource for rheumatologists, pulmonologists, cardiologists, gastroenterologists, nephrologists and all those involved in the care of scleroderma patients.
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Varga, John. \ed.\; Denton, Christopher P. \ed.\; Wigley, Fredrick M. \ed.\; Allanore, Yannick. \ed.\; Kuwana, Masataka. \ed.\
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14.

    Chest Sonography [Electronic resource] / ed. Mathis, Gebhard. - 4th ed. 2017. - [S. l. : s. n.]. - VII, 219 p. 47 illus., 42 illus. in color. - ISBN 9783319440729
    Зміст:

Рубрики: Radiology.
   Respiratory organs—Diseases.
   Thoracic surgery.
   Diagnostic Radiology.
   Pneumology/Respiratory System.
   Thoracic Surgery.
Анотація: This book, widely regarded as the standard work in the field, presents the state of the art in chest sonography with the aid of a wealth of excellent illustrations. It provides the reader with concise, easy-to-assimilate information on all aspects of the use of the modality, including indications, investigative techniques, diagnostic decision making, and imaging artifacts and pitfalls. Numerous tips and tricks and potential sources of diagnostic error are highlighted to aid in daily clinical practice. This fourth edition has been extensively revised to take full account of the latest techniques, study results, and meta-analyses, with inclusion of important additional illustrative material. An entirely new chapter is devoted to interstitial syndrome, and detailed guidance is provided on contrast-enhanced sonography, ultrasound techniques for evaluation of the mediastinum, and the role of chest sonography in emergency medicine. As the value of the technique continues to grow, readers will find Chest Sonography to be a superb up-to-date resource and guide.
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Mathis, Gebhard. \ed.\
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15.

    Popper, Helmut.
    Pathology of Lung Disease [Electronic resource] : morphology – Pathogenesis – Etiology / / Helmut. Popper ; . - 1st ed. 2017. - [S. l. : s. n.]. - XX, 699 p. 670 illus., 632 illus. in color. - ISBN 9783662504918
    Зміст:

Рубрики: Pathology.
   Respiratory organs—Diseases.
   Molecular biology.
   Infectious diseases.
   Oncology  .
   Pathology.
   Pneumology/Respiratory System.
   Molecular Medicine.
   Infectious Diseases.
   Oncology.
Анотація: This well-illustrated textbook covers the full range of lung and pleural diseases from the pathologic standpoint. Both diseases of adults and pediatric lung diseases are presented. The book will serve as an excellent guide to the diagnosis of these diseases, but in addition it explains the disease mechanisms and etiology. Genetics and molecular biology are also discussed whenever necessary for a full understanding. The author is an internationally recognized expert who runs courses on lung and pleural pathology attended by participants from all over the world. In compiling this book, he has drawn on more than 30 years’ experience in the field.
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Popper, Helmut. \.\
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16.

    Pelaia, Girolamo.
    Asthma: Targeted Biological Therapies [Electronic resource] / Girolamo. Pelaia, Vatrella, Alessandro., Maselli, Rosario. ; . - 1st ed. 2017. - [S. l. : s. n.]. - VI, 99 p. 11 illus. in color. - ISBN 9783319460079
Рубрики: Respiratory organs—Diseases.
   Allergy.
   Pharmacology.
   General practice (Medicine).
   Pediatrics.
   Pneumology/Respiratory System.
   Allergology.
   Pharmacology/Toxicology.
   General Practice / Family Medicine.
   Pediatrics.
Анотація: This book focuses on the fundamentals of the use of biologics in asthma, describing the rationale, principles, mechanisms of action, and indications. It offers an excellent balance between basic science and the analysis of clinical trials, updating readers with new developments that are changing the global scenario for targeted biological anti-asthma therapies, especially with regard to more severe disease. A range of therapies are considered, from the humanized monoclonal anti-IgE antibody omalizumab, widely approved as add-on treatment for inadequately controlled disease, through to emerging biologics for which evidence supportive of efficacy is accumulating, including anti-IL-5, anti-IL-4, and anti-IL-13 therapies. One aspect to emerge is the variability in individual response, which suggests a need for characterization of different asthma subtypes to permit the effective implementation of phenotype-targeted treatments. This book will be of interest for pulmonologists, clinical immunologists, and physicians seeking sound information on these therapies, but also for scientists and pharmacologists wishing to enhance their knowledge of the therapeutic implications of the cellular and molecular mechanisms that underlie severe, uncontrolled asthma.
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Vatrella, Alessandro.; Maselli, Rosario.; Pelaia, Girolamo. \.\
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17.

    Comorbidity in Rheumatic Diseases [Electronic resource] / ed. El Miedany, Yasser. - 1st ed. 2017. - [S. l. : s. n.]. - XV, 433 p. 22 illus., 21 illus. in color. - ISBN 9783319599632
    Зміст:

Рубрики: Rheumatology.
   Orthopedics.
   Rehabilitation medicine.
   Cardiology.
   Respiratory organs—Diseases.
   Rheumatology.
   Orthopedics.
   Rehabilitation Medicine.
   Cardiology.
   Pneumology/Respiratory System.
Анотація: This book explores comorbidity in patients with rheumatic diseases and details both care and treatment options in standard clinical practice.Patients with rheumatic diseases are clinically complex, and the interplay of their disease activity with associated conditions may lead to increased morbidity and mortality. Recently there have been major advances in the management of rheumatic diseases, however, without addressing the potential comorbid conditions, including cardiovascular disease; pulmonary disease; and depression; outcomes remain poor. With its 19 chapters, covering the management of major rheumatic diseases (e.g. rheumatoid arthritis, systemic lupus erythematosus , and osteoarthritis), potential comorbidities and treatment recommendations, as well as possible interactions between conditions; this book addresses the gap between textbook medicine and day to day patients' care. Authors also discuss the new hot issue of the comorbidity index, comparing the standard tools to the recently developed indices and how they can assist the rheumatologists in determining disease burden, prognosis, and comorbidity probability. This book is an ideal clinical guide and reference that enables rheumatologists, internal medicine physicians, and residents to address the full clinical expression of these rheumatic diseases with views towards prevention or early management of comorbid conditions. .
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El Miedany, Yasser. \ed.\
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18.

    Chest Drains in Daily Clinical Practice [Electronic resource] / ed. Kiefer, Thomas. - 1st ed. 2017. - [S. l. : s. n.]. - XII, 202 p. 87 illus., 65 illus. in color. - ISBN 9783319323398
    Зміст:

Рубрики: Respiratory organs—Diseases.
Pneumology/Respiratory System.
Анотація: This book covers all aspects of successfully treating patients using chest drains, beginning with anatomy and ending with physiotherapy and pain management. The aim of the book is to provide medical professionals with a step-by-step guide to using a chest drain, with specific chapters on indications, kinds of chest drains, catheters, drainage systems, how to insert a chest tube, complications during placement and handling of a chest drain, removing a chest drain, management of the pleural space and post-procedural care. Unlike general thoracic surgery textbooks, this book gives a complete overview of chest drains in clinical practice to ensure the best possible care of patients. .
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19.

    Clinical Research and Practice [Electronic resource] / ed. Pokorski, Mieczyslaw. - 1st ed. 2017. - [S. l. : s. n.]. - VIII, 124 p. 17 illus., 7 illus. in color. - ISBN 9783319654454
    Зміст:

Regional Diversification of Influenza Activity in Poland during the 2015/16 Epidemic Season, K. Szymański, D. Kowalczyk, K. Cieślak, L.B Brydak -- Impact of Internal and External Factors on EBC-pH and FeNO Changes in Humans Following Challenge with Ethyl Acrylate, F. Hoffmeyer, K. Sucker, H. Berresheim, C. Monsé, B. Jettkant, A. Beine, M. Raulf, J. Bünger, T. Brüning -- Influence of Socioeconomic Factors on Self-Reported Prevalence of Allergic Diseases among Female University Students, K. Kliś, M. Żurawiecka, A. Suder, I. Teul, B. Borowska-Strugińska, E. Suliga, I. Wronka -- Microbiologic Methods in the Diagnostics of Upper Respiratory Tract Pathogens, J. Kompanikova, A. Zumdick, M. Neuschlova, V. Sadlonova, and E. Novakova -- Seroprevalence of Bartonella Species in Patients with Ocular Inflammation, J. Brydak-Godowska, D. Kopacz, P.K. Borkowski, B. Fiecek, A. Hevelke, D. Rabczenko, S. Tylewska-Wierzbanowska, D. Kęcik, and Tomasz Chmielewski -- Body Composition, Anthropometric Indices and Hydration Status of Obstructive Sleep Apnea Patients: Can Cachexia Coexist with Obesity?, B. Kuźnar-Kamińska, M. Grabicki, T. Trafas, M. Szulińska, S. Cofta, T. Piorunek, B. Brajer-Luftmann, A. Nowicka, B. Bromińska, H. Batura-Gabryel -- Frailty and Primary Sarcopenia: a Review, E. Carmeli -- Exercise Strategies to Counteract Brain Aging Effects, D. Szalewska, M. Radkowski, U. Demkow, P.J. Winklewski -- Evaluation of Immune Indices and Serum Vitamin D Content in Children with Atopic Dermatitis, A. Lipińska-Opałka, A. Wawrzyniak, S. Lewicki, R Zdanowski, B. Kalicki -- Synergistic Activity for Natural and Synthetic Inhibitors of Angiogenesis Induced by Murine Sarcoma L-1 and Human Kidney Cancer Cells, B.J. Bałan, A.K.Siwicki, K. Pastewka, U. Demkow, P. Skopiński, E. Skopińska-Różewska, S. Lewicki, R. Zdanowski -- Solitary Rectal Ulcer Syndrome in Children: A Case Series Study, K. Kowalska-Duplaga, I. Lazowska-Przeorek, K. Karolewska-Bochenek, M. Woynarowski, G. Czaja-Bulsa, A. Stawarski, S. Pieczarkowski, E. Hapyn, J. Jozefczuk, B. Korczowski, A. Szaflarska-Poplawska, A. Banaszkiewicz -- Knee Cartilage Regeneration with Umbilical Cord Mesenchymal Stem Cells Embedded in Collagen Scaffold Using Dry Arthroscopy Technique, B. Sadlik, G. Jaroslawski, D. Gladysz, M. Puszkarz, M. Markowska, K. Pawelec, D. Boruczkowski, T. Oldak -- index.

Рубрики: Respiratory organs—Diseases.
   Neurosciences.
   Neurobiology.
   Pneumology/Respiratory System.
   Neurosciences.
   Neurobiology.
Анотація: This book is a blend of medical research and clinical practice. Advancements in practice are inextricably bound to have research underpinnings. The articles highlight a range of practical topics. The respiratory tract is upfront as the first line of defense of the organism. Virological and bacteriological aspects of the infections that continue to be a scourge worldwide, influenza and tuberculosis, are dealt with. Sleep disordered breathing is another hot topic. Allergy and atopy, and the role of nutraceuticals in providing anticancer benefits due to the inhibitory effects on tumor growth and angiogenesis are referred to. Other chapters describe the use of mesenchymal stem cells for regeneration of the worn away cartilage tissue in the knee. The assessment and management of cognitive decline, sarcopenia and frailty of old age also figure prominently in the texts. The book is an attempt to demonstrate the viability of a bench-to-bedside design in point-of-care patient applications. Hopefully, it will be a source of information on interdisciplinary medical research advancements, addressing the needs of medical professionals, from scientists to clinicians and allied health professionals.
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Pokorski, Mieczyslaw. \ed.\
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20.

    Molecular Allergy Diagnostics [Electronic resource] : innovation for a Better Patient Management / / ed.: Kleine-Tebbe, Jörg., Jakob, Thilo. - 1st ed. 2017. - [S. l. : s. n.]. - XX, 531 p. 112 illus., 100 illus. in color. - ISBN 9783319424996
    Зміст:

Рубрики: Allergy.
   Dermatology.
   Pediatrics.
   Otorhinolaryngology.
   Respiratory organs—Diseases.
   General practice (Medicine).
   Allergology.
   Dermatology.
   Pediatrics.
   Otorhinolaryngology.
   Pneumology/Respiratory System.
   General Practice / Family Medicine.
Анотація: This book, based on a recent German publication, offers an overview of basic data and recent developments in the groundbreaking field of molecular allergology. It comprehensively explores the origin and structure of single allergen molecules ("components") and their utility in improving the management of type I, IgE-mediated allergic reactions and disorders like allergic respiratory diseases, food allergies, and anaphylaxis. Highly specific testing, called component-resolved diagnostics, aims to identify and utilize single molecules. Over 200 single allergens from plant or animal sources have been applied to single or multiplex laboratory testing for the presence of allergen-specific IgE. This leap in assay sensitivity and specificity has led to three major advances in patient management: discrimination between primary allergic sensitization and complex cross-reactivity, recognition of IgE profiles for certain allergens and identification of patients most likely to benefit from allergen-specific immunotherapy. The book discusses in detail the benefits and limitations of this 21st century technology, and offers suggestions for the use of molecular allergology in routine clinical practice. It is a “must read” for physicians treating allergic patients as well as scientists interested in natural allergic molecules and their interactions with the human immune system.
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Kleine-Tebbe, Jörg. \ed.\; Jakob, Thilo. \ed.\
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