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    Plant Aquaporins [Electronic resource] : from Transport to Signaling / / ed.: Chaumont, François., Tyerman, Stephen D. - 1st ed. 2017. - [S. l. : s. n.]. - VIII, 353 p. 30 illus., 29 illus. in color. - ISBN 9783319493954
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Рубрики: Plant physiology.
   Plant biochemistry.
   Proteins .
   Cell membranes .
   Plant Physiology.
   Plant Biochemistry.
   Protein Science.
   Membrane Biology.
Анотація: Aquaporins are channel proteins that facilitate the diffusion of water and small uncharged solutes across cellular membranes. Plant aquaporins form a large family of highly divergent proteins that are involved in many different physiological processes. This book will summarize the recent advances regarding plant aquaporins, their phylogeny, structure, substrate specificity, mechanisms of regulation and roles in various important physiological processes related to the control of water flow and small solute distribution at the cell, tissue and plant level in an ever-changing environment.
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Chaumont, François. \ed.\; Tyerman, Stephen D. \ed.\
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    Lipidomics of Stem Cells [Electronic resource] / ed.: Pébay, Alice., Wong, Raymond C.B. - 1st ed. 2017. - [S. l. : s. n.]. - XIII, 212 p. 24 illus., 22 illus. in color. - ISBN 9783319493435
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Рубрики: Stem cells.
   Lipids.
   Cell physiology.
   Cell membranes .
   Stem Cells.
   Lipidology.
   Cell Physiology.
   Membrane Biology.
Анотація: This book combines the current knowledge on the role of lipids in stem cell pluripotency and differentiation. It showcases various approaches to the study of lipids and focuses on various types of stem cells and specific lipids driving maintenance or differentiation. The volume includes chapters reviewing roles of specific lipids in pluripotency, neurogenesis and exocytosis as well as in cancer stem cells. Examples of different classes of lipids—such as sphingolipids, lysophospholipids, cannabinoids and neutral lipids—are described and illustrate the vast biological effects of this class of molecules. The international contributors are all recognized experts in their respective fields. Covering the various aspects of the topic, Lipidomics of Stem Cells provides an up-to-date snapshot—unique among the literature—of where the lipid world is in terms of understanding the roles of lipids in stem cell biology. It provides an essential reference for stem cell biologists, lipid biologists, development biologists, students, academics and clinicians in related areas.
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Pébay, Alice. \ed.\; Wong, Raymond C.B. \ed.\
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    Pollen Tip Growth [Electronic resource] : from Biophysical Aspects to Systems Biology / / ed.: Obermeyer, Gerhard., Feijó, José. - 1st ed. 2017. - [S. l. : s. n.]. - VIII, 424 p. 57 illus., 47 illus. in color. - ISBN 9783319566450
    Зміст:

Рубрики: Plant biochemistry.
   Systems biology.
   Biological systems.
   Cell membranes .
   Plant Biochemistry.
   Systems Biology.
   Systems Biology.
   Membrane Biology.
Анотація: This book focuses on the biophysical aspects of tip growth: How do physical parameters like pressure, water potential, electrical fields, or ion currents contribute to and influence this specialized and highly dynamic form of cell growth? It provides an updated and balanced overview of the current state of knowledge and future research perspectives regarding how pollen tubes’ growth is driven and regulated by molecular interactions underlying the cellular processes. The individual chapters address topics ranging from molecular biophysical concepts to comprehensive omic studies and computational modeling of the tip growth process. In addition, a chapter on root hair cells is included to provide an alternative view on the underlying molecular principles of tip growth in general. Each chapter provides a summary of cutting-edge techniques, results and experimental data; a statement, hypothesis or conclusion on the importance of the aspect described for tip growth, particularly pollen tip growth; and addresses open gaps in our understanding and potential approaches to remedying them. The book offers experimental and theoretical solutions to help established researchers and newcomers to the field alike solve the many mysterious behaviors of pollen tube tips.
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Obermeyer, Gerhard. \ed.\; Feijó, José. \ed.\
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    Membrane Dynamics and Calcium Signaling [Electronic resource] / ed. Krebs, Joachim. - 1st ed. 2017. - [S. l. : s. n.]. - VIII, 412 p. 59 illus. in color. - ISBN 9783319558585
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Рубрики: Cell membranes .
   Proteins .
   Biophysics.
   Biological physics.
   Membrane Biology.
   Protein-Ligand Interactions.
   Biological and Medical Physics, Biophysics.
Анотація: This book describes the newest discoveries on calcium signaling happening at the cellular and intracellular membranes, often exerted in so called microdomains. Calcium entry and release, its interaction with proteins and resulting events on proteins and organelles are comprehensively depicted by leading experts in the field. Knowledge about details of these highly dynamic processes rapidly increased in recent years, the book therefore provides a timely summary on the processes of calcium signaling and related membrane dynamics; it is aimed at students and researchers in biochemistry and cell biology.
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    Molecules, Systems and Signaling in Liver Injury [Electronic resource] / ed.: Ding, Wen-Xing., Yin, Xiao-Ming. - 1st ed. 2017. - [S. l. : s. n.]. - XV, 290 p. 25 illus., 20 illus. in color. - ISBN 9783319581064
Рубрики: Cell cycle.
   Apoptosis.
   Cell physiology.
   Hepatology.
   Cell membranes .
   Cell Cycle Analysis.
   Apoptosis.
   Cell Physiology.
   Hepatology.
   Membrane Biology.
Анотація: This essential volume presents comprehensive information on cell death and autophagy in liver diseases, including the role and molecular signaling pathways of cell death in alcohol and non-alcoholic fatty liver disease, bile acids, hepatitis C virus and drug-induced liver injury. The book starts with a discussion of lipotoxicity in non-parenchymal cells, followed by a discussion of cell death and autophagy in cholangiocytes, hepatic stellate cells and Kupffer cells in hepatic biliary diseases, fibrosis and liver inflammation. The book also covers Bcl-2 family proteins, beta-catenin and HMGB1 signaling in regulating cell death in the liver as well as mitochondria, ER stress and gut microbiota on liver injury. The Cell Death in Biology and Diseases series has recruited world experts ranging from basic scientists to clinicians on cell death in liver diseases. Likewise the contributors of this volume are leaders in their fields with worldwide expertise and perspective. Molecules, Systems and Signaling in Liver Injury is an essential companion to Hepatocytes and Non-Parenchymal Cells and Diseases. It is beneficial for both clinicians and basic scientists and is relevant to those working on drug discovery for preventing and treating liver diseases by targeting cell death and autophagy pathways.
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Ding, Wen-Xing. \ed.\; Yin, Xiao-Ming. \ed.\
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    The Blood Brain Barrier and Inflammation [Electronic resource] / ed.: Lyck, Ruth., Enzmann, Gaby. - 1st ed. 2017. - [S. l. : s. n.]. - VI, 286 p. 32 illus., 24 illus. in color. - ISBN 9783319455143
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Рубрики: Immunology.
   Neurosciences.
   Cell membranes .
   Infectious diseases.
   Cytokines.
   Growth factors.
   Immunology.
   Neurosciences.
   Membrane Biology.
   Infectious Diseases.
   Cytokines and Growth Factors.
Анотація: Within the central nervous system (CNS) the constantly changing blood stream is separated from the CNS parenchyma by the blood brain barrier (BBB) restricting passage to selected immune cells. Under pathological conditions, however, viruses, bacteria, parasites and autoaggressive immune cells can penetrate the barrier and contribute to CNS inflammation. The BBB actively contributes to neuroinflammation by presentation of chemokines, expression of cell adhesion molecules and alteration of barrier properties. As such, understanding the role of the BBB under healthy and pathological conditions is essential for the development of new drugs to efficiently combat inflammatory diseases of the CNS. This book presents a comprehensive collection of reviews that focus on the role of the BBB. Experts in the field share their insight on structural, topological and functional properties of the BBB. They elaborate on pathophysiological changes of the inflamed BBB such as permeability, transporter proteins and alterations in microRNAs and cytokine profile. Additional chapters on multiple sclerosis and bacterial meningitis provide in depth information on significant neuroinflammatory diseases. The selection is complemented by a review on the current understanding of the BBB as signaling hub in tumor pathogenesis in the brain.
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Lyck, Ruth. \ed.\; Enzmann, Gaby. \ed.\
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    Cellular Injury in Liver Diseases [Electronic resource] / ed.: Ding, Wen-Xing., Yin, Xiao-Ming. - 1st ed. 2017. - [S. l. : s. n.]. - XIII, 263 p. 26 illus., 22 illus. in color. - ISBN 9783319537740
    Зміст:

Рубрики: Cell cycle.
   Apoptosis.
   Cell physiology.
   Hepatology.
   Cell membranes .
   Cell Cycle Analysis.
   Apoptosis.
   Cell Physiology.
   Hepatology.
   Membrane Biology.
Анотація: This comprehensive volume describes drug and virus-mediated hepatocyte injury, alcohol, lipid and bile acid-induced hepatocyte injury in addition to ischemia-reperfusion-mediated liver injury. The chapter authors who discuss these topics are leading experts on cell death in liver diseases. The authors link these different types of liver injury to the commonly associated liver inflammation, fibrosis and tumorigenesis. Other topics explored include the various forms of cell death and cell survival pathways that have been identified in the liver, such as apoptosis, necroptosis, pryoptosis and autophagy. This book, along with its companion volume, Molecules, Systems and Signaling in Hepatic Cell Death, provides a thorough and comprehensive discussion on the topic of cell death and liver disease. Cellular Injury in Liver Diseases is an essential addition to the Cell Death in Biology and Diseases series and will appeal to scientists, clinicians and those doing research for drug discovery. .
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Ding, Wen-Xing. \ed.\; Yin, Xiao-Ming. \ed.\
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    Candida albicans: Cellular and Molecular Biology [Electronic resource] / ed. Prasad, Rajendra. - 2nd ed. 2017. - [S. l. : s. n.]. - XII, 554 p. 60 illus., 30 illus. in color. - ISBN 9783319504094
    Зміст:

Рубрики: Mycology.
   Molecular biology.
   Drug resistance.
   Cell membranes .
   Mycology.
   Molecular Medicine.
   Drug Resistance.
   Membrane Biology.
Анотація: This book on Candida albicans and similar pathogens provides a timely overview of the groundbreaking discoveries made in the areas of drug resistance, host–pathogen interactions, virulence, host immune system modulation, etc., in the last two decades. This comprehensive 2nd Edition includes chapters on fungal infections, hyphal morphogenesis, molecular mechanisms of antifungal resistance, antifungal agents, multidrug transporters, virulence mechanisms in Candida albicans, host–pathogen interactions, the cell wall, fungal biofilms, lipids and antifungal resistance, signaling mechanisms and last but not the least host-immune responses. As such, it offers an ideal reference guide for mycologists, researchers, pharmacists, clinicians, and undergraduate students engaged or interested in fungal research. It will also benefit clinicians, who are required to keep abreast of the current state of research on antifungal drug resistance and antifungal development.
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    Membrane Organization and Dynamics [Electronic resource] / ed. Chattopadhyay, Amitabha. - 1st ed. 2017. - [S. l. : s. n.]. - IX, 387 p. 89 illus., 67 illus. in color. - ISBN 9783319666013
Рубрики: Cell membranes .
   Biophysics.
   Biological physics.
   Lipids.
   Proteins .
   Membrane Biology.
   Biological and Medical Physics, Biophysics.
   Lipidology.
   Protein Science.
Анотація: This volume brings together information on membrane organization and dynamics from a variety of spectroscopic, microscopic and simulation approaches, spanning a broad range of time scales. The implication of such dynamic information on membrane function in health and disease is a topic of contemporary interest. The chapters cover various aspects of membrane lipid and protein dynamics, explored using a battery of experimental and theoretical approaches. The synthesis of information and knowledge gained by utilizing multiple approaches will provide the reader with a comprehensive understanding of the underlying membrane dynamics and function, which will help to develop robust dynamic models for the understanding of membrane function in healthy and diseased states. In the last few years, crystal structures of an impressive number of membrane proteins have been reported, thanks to tremendous advances in membrane protein crystallization techniques. Some of these recently solved structures belong to the G protein-coupled receptor (GPCR) family, which are particularly difficult to crystallize due to their intrinsic flexibility. Nonetheless, these static structures do not provide the necessary information to understand the function of membrane proteins in the complex membrane milieu. This volume will address the dynamic nature of membrane proteins within the membrane and will provide the reader with an up-to date overview of the theory and practical approaches that can be used. This volume will be invaluable to researchers working in a wide range of scientific areas, from biochemistry and molecular biology to biophysics and protein science. Students of these fields will also find this volume very useful. This book will also be of great use to those who are interested in the dynamic nature of biological processes. .
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10.

    The Biophysics of Cell Membranes [Electronic resource] : biological Consequences / / ed.: Epand, Richard M., Ruysschaert, Jean-Marie. - 1st ed. 2017. - [S. l. : s. n.]. - VII, 219 p. 49 illus., 32 illus. in color. - ISBN 9789811062445
    Зміст:

Рубрики: Cell membranes .
   Biophysics.
   Biological physics.
   Bioorganic chemistry.
   Medical genetics.
   Membrane Biology.
   Biological and Medical Physics, Biophysics.
   Bioorganic Chemistry.
   Gene Function.
Анотація: This volume focuses on the modulation of biological membranes by specific biophysical properties. The readers are introduced to emerging biophysical approaches that mimick specific states (like membrane lipid asymmetry, membrane curvature, lipid flip-flop, lipid phase separation) that are relevant to the functioning of biological membranes. The first chapter describes innovative methods to mimic the prevailing asymmetry in biological membranes by forming asymmetrical membranes made of monolayers with different compositions. One of the chapters illustrates how physical parameters, like curvature and elasticity, can affect and modulate the interactions between lipids and proteins. This volume also describes the sensitivity of certain ion channels to mechanical forces and it presents an analysis of how cell shape is determined by both the cytoskeleton and the lipid domains in the membrane. The last chapter provides evidence that liposomes can be used as a minimal cellular model to reconstitute processes related to the origin of life. Each topic covered in this volume is presented by leading experts in the field who are able to present clear, authoritative and up-to-date reviews. The novelty of the methods proposed and their potential for a deeper molecular description of membrane functioning are particularly relevant experts in the areas of biochemistry, biophysics and cell biology, while also presenting clear and thorough introductions, making the material suitable for students in these fields as well.
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Epand, Richard M. \ed.\; Ruysschaert, Jean-Marie. \ed.\
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11.

    Wardhan, Rashmi.
    Textbook of Membrane Biology [Electronic resource] / Rashmi. Wardhan, Mudgal, Padmshree. ; . - 1st ed. 2017. - [S. l. : s. n.]. - XXV, 368 p. 343 illus. - ISBN 9789811071010
    Зміст:

Рубрики: Cell membranes .
   Proteins .
   Cell physiology.
   Membrane Biology.
   Protein-Ligand Interactions.
   Receptors.
   Protein Science.
   Cell Physiology.
Анотація: This book provides a comprehensive overview of the basic principles, concepts, techniques and latest advances in the field of biomembranes and membrane-associated processes. With new emerging technologies and bioinformatics tools, this is a promising area for future study and research. The book discusses the composition, fluidity and dynamic nature of phospholipid bilayers, which vary with cell/organelle type and function. It describes the various types of transport proteins that facilitate the transport of polar and nonpolar molecules across the membrane actively or passively via ion-channels or through porins. It also explores the many cellular functions membranes participate in: (1) energy transduction, which includes the electron transport chain in inner membrane of mitochondria and bacterial cytoplasmic membrane and photosynthetic electron transport in thylakoid membranes in chloroplast and photosynthetic bacterial membranes; (2) cell–cell communication involving various signal transduction pathways triggered by activated membrane receptors; (3) cell–cell interactions involving various types of adhesion and receptor proteins; (4) nerve transmission involving opening and closing of voltage gated ionic channels; and (5) intracellular transport involving the processes of endocytosis, exocytosis, vesicular transport of solutes between intracellular compartments, membrane fusion and membrane biogenesis.
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Mudgal, Padmshree.; Wardhan, Rashmi. \.\
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12.

    Aquaporins [Electronic resource] / ed. Yang, Baoxue. - 1st ed. 2017. - [S. l. : s. n.]. - XII, 278 p. 69 illus., 59 illus. in color. - ISBN 9789402410570
    Зміст:

Рубрики: Pharmacology.
   Proteins .
   Human physiology.
   Cell membranes .
   Pharmacology/Toxicology.
   Protein Science.
   Human Physiology.
   Membrane Biology.
Анотація: This book provides a state-of-the-art report on our current understanding of aquaporins and the future direction of the field. Aquaporins (AQPs) are a group of water-channel proteins that are specifically permeable to water and other small molecules, such as glycerol and urea. To date thirteen water-channel proteins (AQP0 – AQP12) have been cloned and the mechanisms and physiological functions of water transport across biological membranes have long been the subject of interest. Recent advances in the molecular biology and physiology of water transport have yielded new insights into how and why water moves across cell membranes, and studies on aquaporin knockout mouse models suggest that aquaporins are involved in the development of some diseases and they may be useful targets of research into selective-inhibitor drugs. By focusing on the advances made over the last 20 years in the biophysics, genetics, protein structure, molecular biology, physiology, pathophysiology and pharmacology of aquaporins in mammalian cell membranes, this book provides novel insights into further mechanisms and the physiological significance of water and some small molecule transport in mammals in order to stimulate further research in new directions.
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Yang, Baoxue. \ed.\
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