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1.


   
    Transgenesis and Secondary Metabolism [Electronic resource] / ed. Jha, Sumita. - 1st ed. 2017. - [S. l. : s. n.]. - 108 illus., 65 illus. in color. eReference. - ISBN 9783319286693
    Зміст:
Рубрики: Genetic engineering.
   Plant genetics.
   Plant biochemistry.
   Metabolism.
   Bioorganic chemistry.
   Pharmacy.
   Genetic Engineering.
   Plant Genetics and Genomics.
   Plant Biochemistry.
   Metabolomics.
   Bioorganic Chemistry.
   Pharmacy.
Анотація: This handbook provides comprehensive reference information on the efficient production of secondary metabolites from plants by transgenesis and other genetic manipulation strategies. It reviews and summarizes selected important case studies in genetic methods applied to enhance the production of a given metabolite or a group of related or derived compounds. Readers will find reference information on a multitude of techniques and methods, including traditional breeding and screening; over-expression of genes encoding key enzymes; functional genomics approaches; metabolic engineering of the relevant biosynthetic pathways; indirect genetic approaches to improve metabolite production, including Agrobacterium mediated transformations. Furthermore, combinatorial biochemistry approaches to engineer secondary metabolic pathways are summarized, which can offer access to new structures or to the design of novel compounds. Since many commercially valuable substances are still extracted from plants, being largely inaccessible to efficient modern laboratory synthesis methods, this book provides a valuable resource of information for biotechnological approaches that can help to find alternative and more efficient methods for the production of natural secondary metabolites. Thus adjusted production methods, with the help of tailored plant systems, can potentially help to release the stress on plants, which are currently suffering from extensive human harvesting, and to conserve global biodiversity. Readers will find comprehensive reference information on plant genetic manipulation toward more efficient synthesis, accumulation and production of target secondary metabolites. The handbook will appeal to researchers and professionals, but also graduate students and scholars working in the fields of biotechnology, genetic engineering, medicinal plant research, pharmacy, and phytochemistry.
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2.


    Jeffers, Joe S.
    Frederick Sanger [Electronic resource] : two-Time Nobel Laureate in Chemistry / / Joe S. Jeffers ; . - 1st ed. 2017. - [S. l. : s. n.]. - XI, 88 p. 70 illus., 23 illus. in color. - ISBN 9783319547091
    Зміст:
Рубрики: Bioorganic chemistry.
   History.
   Proteins .
   Bioorganic Chemistry.
   History of Science.
   Protein Science.
Анотація: In this Brief, Joe Jeffers uncovers the life and works of two-time Nobel Laureate Frederick Sanger. Following Sanger’s early life to retirement, Jeffers describes how this celebrated British biochemist became the first person to determine the amino acid sequence of a protein for which he was awarded the Nobel Prize in 1958. Highlighting Sanger’s remarkable career, Jeffers describes Sanger’s later change in research direction to investigate deoxyribonucleic acids (DNA), work for which Sanger also received the Nobel Prize jointly with Paul Berg and Walter Gilbert in 1980. Joe Jeffers conducted twelve interviews with Sanger over the period of 1999-2009 and he has also spoken to more than 40 of Sanger’s colleagues and family members. This brief provides a rigorous yet concise view of Sanger on a personal and scientific level and is suitable for biochemists, historians or the interested layperson.
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3.


   
    Phosphate Labeling and Sensing in Chemical Biology [Electronic resource] / ed. Jessen, Henning Jacob. - 1st ed. 2017. - [S. l. : s. n.]. - VIII, 239 p. 87 illus., 60 illus. in color. - ISBN 9783319603575
    Зміст:
Рубрики: Bioorganic chemistry.
   Proteins .
   Nucleic acids.
   Cell biology.
   Bioorganic Chemistry.
   Protein Science.
   Nucleic Acid Chemistry.
   Cell Biology.
Анотація: The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.
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4.


    Morgan, Sarah Elizabeth.
    Ultrafast Quantum Effects and Vibrational Dynamics in Organic and Biological Systems [Electronic resource] / Sarah Elizabeth. Morgan ; . - 1st ed. 2017. - [S. l. : s. n.]. - XV, 110 p. 72 illus., 65 illus. in color. - ISBN 9783319633992
    Зміст:
Рубрики: Spectroscopy.
   Microscopy.
   Biophysics.
   Biological physics.
   Bioorganic chemistry.
   Energy harvesting.
   Atomic structure  .
   Molecular structure .
   Surfaces (Physics).
   Interfaces (Physical sciences).
   Thin films.
   Spectroscopy and Microscopy.
   Biological and Medical Physics, Biophysics.
   Bioorganic Chemistry.
   Energy Harvesting.
   Atomic/Molecular Structure and Spectra.
   Surface and Interface Science, Thin Films.
Анотація: This thesis focuses on theoretical analysis of the sophisticated ultrafast optical experiments that probe the crucial first few picoseconds of quantum light harvesting, making an important contribution to quantum biology, an exciting new field at the intersection of condensed matter, physical chemistry and biology. It provides new insights into the role of vibrational dynamics during singlet fission of organic pentacene thin films, and targeting the importance of vibrational dynamics in the design of nanoscale organic light harvesting devices, it also develops a new wavelet analysis technique to probe vibronic dynamics in time-resolved nonlinear optical experiments. Lastly, the thesis explores the theory of how non-linear “breather” vibrations are excited and propagate in the disordered nanostructures of photosynthetic proteins.   .
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5.


   
    Measurement, Modeling and Automation in Advanced Food Processing [Electronic resource] / ed. Hitzmann, Bernd. - 1st ed. 2017. - [S. l. : s. n.]. - VII, 198 p. - ISBN 9783319601113
    Зміст:
Рубрики: Food—Biotechnology.
   Chemical engineering.
   Biotechnology.
   Bioorganic chemistry.
   Food Science.
   Industrial Chemistry/Chemical Engineering.
   Biotechnology.
   Bioorganic Chemistry.
Анотація: This book review series presents current trends in modern biotechnology. The aim is to cover all aspects of this interdisciplinary technology where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science. Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification. In general, special volumes are edited by well-known guest editors. The series editor and publisher will however always be pleased to receive suggestions and supplementary information. Manuscripts are accepted in English.
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Hitzmann, Bernd. \ed.\
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6.


    Dutta, Pradip K.
    Optically Active Polymers [Electronic resource] : a Systematic Study on Syntheses and Properties / / Pradip K. Dutta, Kumar, Vinod. ; . - 1st ed. 2017. - [S. l. : s. n.]. - XIX, 47 p. 12 illus. - ISBN 9789811026065
    Зміст:
Рубрики: Polymers  .
   Bioorganic chemistry.
   Biochemical engineering.
   Polymer Sciences.
   Bioorganic Chemistry.
   Biochemical Engineering.
Анотація: The brief presents a systematic study of synthesis of optically active polymers. It discusses in detail about the synthesis of three different types of optically active polymers from helical polymers, dendronized polymers and other types of polymeric compounds. The brief also explains the synthesis of optically active azoaromatic and carbazole containing azoaromatic polymers and copolymers; optically active benzodithiophene; and optically active porphyrin derivatives. The final chapter of the brief discusses different properties of optically active polymers such as nonlinear optical properties, chiroptical properties, vapochromic behavior, absorption and emission properties, fabrication, and photochromic properties. The intrinsic details of different properties of optically active polymers presented in this work will be useful for researchers and industry personnel, who are actively engaged in application oriented investigations.
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Kumar, Vinod.; Dutta, Pradip K. \.\
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7.


    Terasaka, Naohiro.
    Applications of Aminoacylation Ribozymes That Recognize the 3′-end of tRNA [Electronic resource] / Naohiro. Terasaka ; . - 1st ed. 2017. - [S. l. : s. n.]. - XII, 89 p. 38 illus., 28 illus. in color. - ISBN 9784431565178
    Зміст:
Рубрики: Bioorganic chemistry.
   Catalysis.
   Nucleic acids.
   Biotechnology.
   Bioorganic Chemistry.
   Catalysis.
   Nucleic Acid Chemistry.
   Biotechnology.
Анотація: In this thesis, applications of aminoacylation ribozymes named flexizymes are described. Flexizymes have the following unique characteristics: (i) substrate RNA is recognized by two consecutive base pairs between the 3'-end of substrate RNA and the 3'-end of the flexizyme; (ii) these base pairs can be substituted with other base pairs; and (iii) various activated amino acids can be used as substrates including both canonical and noncanonical amino acids. This flexible aminoacylation of RNAs by flexizymes was used to label endogenous tRNAs to be removed, and in vitro selection using the tRNA-depleted library enabled the discovery of the novel interaction between the microRNA precursor and metabolites. Flexizymes are also used to prepare various aminoacyl-tRNAs bearing mutations at the 3'-end to engineer the translation machinery and to develop the orthogonal translation machinery. The first part of the research demonstrated that SELEX is appropriate for discovering the interaction between small RNA and ligands, and suggested that more RNA motif binding to small molecules exists in small RNAs. The second part opened a door to new opportunities for in vitro synthetic biology involving the engineering of the genetic codes and translation machineries. This research also indicated the great potential of aminoacylation by flexizymes to be applied in various fields of RNA research, which is beneficial for RNA researchers.
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8.


   
    The Biophysics of Cell Membranes [Electronic resource] : biological Consequences / / ed.: Epand, Richard M., Ruysschaert, Jean-Marie. - 1st ed. 2017. - [S. l. : s. n.]. - VII, 219 p. 49 illus., 32 illus. in color. - ISBN 9789811062445
    Зміст:
Рубрики: Cell membranes .
   Biophysics.
   Biological physics.
   Bioorganic chemistry.
   Medical genetics.
   Membrane Biology.
   Biological and Medical Physics, Biophysics.
   Bioorganic Chemistry.
   Gene Function.
Анотація: This volume focuses on the modulation of biological membranes by specific biophysical properties. The readers are introduced to emerging biophysical approaches that mimick specific states (like membrane lipid asymmetry, membrane curvature, lipid flip-flop, lipid phase separation) that are relevant to the functioning of biological membranes. The first chapter describes innovative methods to mimic the prevailing asymmetry in biological membranes by forming asymmetrical membranes made of monolayers with different compositions. One of the chapters illustrates how physical parameters, like curvature and elasticity, can affect and modulate the interactions between lipids and proteins. This volume also describes the sensitivity of certain ion channels to mechanical forces and it presents an analysis of how cell shape is determined by both the cytoskeleton and the lipid domains in the membrane. The last chapter provides evidence that liposomes can be used as a minimal cellular model to reconstitute processes related to the origin of life. Each topic covered in this volume is presented by leading experts in the field who are able to present clear, authoritative and up-to-date reviews. The novelty of the methods proposed and their potential for a deeper molecular description of membrane functioning are particularly relevant experts in the areas of biochemistry, biophysics and cell biology, while also presenting clear and thorough introductions, making the material suitable for students in these fields as well.
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Epand, Richard M. \ed.\; Ruysschaert, Jean-Marie. \ed.\
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9.


    Ježek, Jan.
    Biomedical Applications of Acridines [Electronic resource] : derivatives, Syntheses, Properties and Biological Activities with a Focus on Neurodegenerative Diseases / / Jan. Ježek, Hlaváček, Jan., Šebestík, Jaroslav. ; . - 1st ed. 2017. - [S. l. : s. n.]. - XIII, 237 p. 79 illus., 25 illus. in color. - ISBN 9783319639536
    Зміст:
Рубрики: Medicinal chemistry.
   Neurochemistry.
   Pharmacology.
   Proteins .
   Bioorganic chemistry.
   Nucleic acids.
   Medicinal Chemistry.
   Neurochemistry.
   Pharmacology/Toxicology.
   Protein-Ligand Interactions.
   Bioorganic Chemistry.
   Nucleic Acid Chemistry.
Анотація: This book describes applications of acridines for the treatment of various neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease, and various prion diseases, and discusses the potential of acridines in neuro-regenerative medicine. Using modern data-mining software, it presents structures of acridines with nucleic acids and proteins and compares them with the native structures. Furthermore, the book presents modern methods of acridine synthesis, comparing them with the most useful conventional methods. Acridines interact with both nucleic acids and proteins, and due to their direct interactions with various enzymes, they can be suitable for the treatment of neurodegenerative diseases, inflammation, immunological disorders, and protozoal diseases. The characteristic spectral properties of acridines can  be employed in labeling proteins, nucleic acids, lipids, and even cells and their compartments. Moreover, they can be applied in photodynamic therapy.
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Hlaváček, Jan.; Šebestík, Jaroslav.; Ježek, Jan. \.\
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10.


   
    Rubber Based Bionanocomposites [Electronic resource] : preparation / / ed. Visakh P. M. - 1st ed. 2017. - [S. l. : s. n.]. - VII, 216 p. 95 illus., 37 illus. in color. - ISBN 9783319488066
    Зміст:
Рубрики: Ceramics.
   Glass.
   Composites (Materials).
   Composite materials.
   Nanotechnology.
   Bioorganic chemistry.
   Biomaterials.
   Ceramics, Glass, Composites, Natural Materials.
   Nanotechnology and Microengineering.
   Bioorganic Chemistry.
   Biomaterials.
Анотація: Leading researchers from industry, academy, government and private research institutions across the globe have contributed to this book, which presents all types of rubber blend composites based on biomaterials as well as nanocomposites. It discusses the fundamental preparation methods of these materials and summarizes many of the latest technical research advances, offering an essential guide for academics, researchers, scientists, engineers and students alike. .
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11.


   
    Glucosinolates [Electronic resource] / ed.: Mérillon, Jean-Michel., Ramawat, Kishan Gopal. - 1st ed. 2017. - [S. l. : s. n.]. - 83 illus., 49 illus. in color. eReference. - ISBN 9783319254623
    Зміст:
Рубрики: Bioorganic chemistry.
   Plant biochemistry.
   Food—Biotechnology.
   Pharmacology.
   Medical biochemistry.
   Plant breeding.
   Bioorganic Chemistry.
   Plant Biochemistry.
   Food Science.
   Pharmacology/Toxicology.
   Medical Biochemistry.
   Plant Breeding/Biotechnology.
Анотація: This is the first comprehensive reference compilation on the substance class of glucosinolates. This handbook introduces the reader to the sulfur-containing glucosinolates (S-glucosides), a class of secondary metabolites of almost all plants of the order Capparales, in particular in the family Brassicaceae (e.g. broccoli and other cabbages), derived from glucose and an amino acid. The book illustrates the natural variety of glucosinolate structures, mainly derived from the precursor amino acid. Chapters describe the resulting rich bioactivity of the glucosides, for example as anti-cancer agents, insecticides, nematicides, fungicides, their potential phytotoxic effects, antimicrobial activity and their possible role in neurodegenerative diseases and human health. Different methods for the extraction, characterization, quantification and processing of the glucosinolates are introduced, and potential applications are discussed. The fate of glucosinolates during food processing is also briefly addressed. This handbook is written by leading experts and structured in different sections addressing the natural occurrence of glucosinolates, their (bio-)synthesis, bioactivity, food processing of glucosinolate-containing vegetables, health and disease-related aspects, biotechnology, and methods applied in glucosinolate-research. It is thus a rich reference source for every reader working in the field, from chemists and biotechnologists, to life scientists, pharmacists and medical scientists.
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Mérillon, Jean-Michel. \ed.\; Ramawat, Kishan Gopal. \ed.\
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12.


   
    Fungal Metabolites [Electronic resource] / ed.: Mérillon, Jean-Michel., Ramawat, Kishan Gopal. - 1st ed. 2017. - [S. l. : s. n.]. - 164 illus., 83 illus. in color. eReference. - ISBN 9783319250014
    Зміст:
Рубрики: Bioorganic chemistry.
   Plant biochemistry.
   Biotechnology.
   Mycology.
   Proteins .
   Plant breeding.
   Bioorganic Chemistry.
   Plant Biochemistry.
   Biotechnology.
   Mycology.
   Protein Science.
   Plant Breeding/Biotechnology.
Анотація: This handbook compiles authoritative information about fungal metabolites and their chemistry and biotechnology. The first in the reference work series “Phytochemicals”, and written by a team of international expert authors, this book provides reference information ranging from the description of fungal natural products, over their use e.g. as anticancer agents, to microbial synthesis, even spanning to the production of secondary metabolites on industrial scale. On the other hand it also describes global health issues related to aflatoxin production in foods and agriculture, including perspectives for detoxification. The handbook characterizes different compound classes derived from fungal secondary metabolites, like ergot alkaloids and aflatoxins. The discussion puts a special emphasis on how potentially useful compounds can be obtained and what applications they can find, on the one hand, and how potential dangers can be encountered on the other hand. The comprehensive chapters in this handbook will thus appeal to readers from diverse backgrounds in chemistry, biology, life sciences, and even medicine, who are working or planning to work with fungal (secondary) metabolites and their application. They provide the readers with rich sources of reference information on important topics in this field.
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13.


    Yoo, Young Je.
    Fundamentals of Enzyme Engineering [Electronic resource] / Young Je. Yoo, Feng, Yan., Kim, Yong-Hwan., Yagonia, Camila Flor J. ; . - 1st ed. 2017. - [S. l. : s. n.]. - X, 209 p. 95 illus., 11 illus. in color. - ISBN 9789402410266
    Зміст:
Рубрики: Biochemical engineering.
   Proteins .
   Bioorganic chemistry.
   Biochemical Engineering.
   Protein Science.
   Bioorganic Chemistry.
Анотація: This book provides a comprehensive introduction to all aspects of enzyme engineering, from fundamental principles through to the state-of-the-art in research and industrial applications. It begins with a brief history, describing the milestones of advancement in enzyme science and technology, before going on to cover the fundamentals of enzyme chemistry, the biosynthesis of enzymes and their production. Enzyme stability and the reaction kinetics during enzymatic reactions are presented to show how enzymes function during catalysis and the factors that affect their activity. Methods to improve enzyme performance are also presented, such as cofactor regeneration and enzyme immobilization. The book emphasizes and elaborates on the performance and characteristics of enzymes at the molecular level. Finally, the book presents recent advances in enzyme engineering and some key industrial application of enzymes addressing the present needs of society. This book presents essential information not only for undergraduate and graduate students, but also for researchers in academia and industry, providing a valuable reference for the development of commercial applications of enzyme technology.
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Feng, Yan.; Kim, Yong-Hwan.; Yagonia, Camila Flor J.; Yoo, Young Je. \.\
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