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Загальна кількість знайдених документів : 13
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Форма документа : Однотомне видання
Шифр видання :
Автор(и) : Bakris George L., Hahr, Allison., Khardori, Romesh., Koya, Daisuke., Molitch, Mark., Prischl, Friedrich C., Schernthaner, Guntram., Thajudeen, Bijin.
Назва : Managing Diabetic Nephropathies in Clinical Practice . -1st ed. 2017.
Вихідні дані : Б.м.,Б.р.
Кільк.характеристики :XV, 129 p. 8 illus. in color.
ISBN, Ціна 9783319088730: Б.ц.
Предметні рубрики: Diabetes.
Nephrology.
Diabetes.
Nephrology.
Зміст : Overview -- Stages of disease and clinical features -- Pathogenesis and pathophysiology -- Patient assessment -- Treatment options.
Анотація: An overview of the diagnosis, treatment, and long-term management of diabetic-related kidney disease in clinical practice. Includes an evidence-based discussion of currently available and experimental drug therapies currently in development, guided by international consensus guidelines. Ideal for physicians, medical trainees, nurses and other medical professional that regularly screen and treat patients with all types of diabetes. Есть полнотекстовые версии (для доступа требуется авторизация)
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Форма документа : Однотомне видання
Шифр видання :
Назва : Diabetes Mellitus in Developing Countries and Underserved Communities . -1st ed. 2017.
Вихідні дані : Б.м.,Б.р.
Кільк.характеристики :XV, 294 p. 65 illus., 49 illus. in color.
ISBN, Ціна 9783319415598: Б.ц.
Предметні рубрики: Diabetes.
Endocrinology .
Diabetes.
Endocrinology.
Зміст : Global Burden of Diabetes: An Overview -- Primary Prevention of Diabetes: An Imperative for Developing Countries -- Diabetes in Sub-Saharan Africa -- Diabetes in the Middle East and North Africa -- Diabetes in China and Western Pacific Region -- Diabetes in India and Southeast Asia -- Diabetes in Latin America -- Diabetes in the Caribbean -- Diabetes in Indigenous Australians and other underserved communities in Australia -- Diabetes among Māori and other ethnic groups in New Zealand -- Diabetes in Eastern Europe -- Diabetes in Immigrant and Minority Populations in Western Europe -- Diabetes among Indigenous Canadians -- Diabetes in Native Populations and Underserved Communities in the United States.
Анотація: Adopting a truly global perspective and a practical approach to diabetes—including pathophysiology, genetics, regional peculiarities, management, prevention and best practices—this book is an excellent resource for clinicians and policy-makers working with patients in more austere settings. The global prevalence of diabetes is estimated to increase from 422 million in 2014 to 592 million in 2035. Sadly, low- and middle-economy countries are projected to experience the steepest increase, but even in developed economies, vulnerable demographic subgroups manifest disparities in diabetes prevalence, quality of care, and outcomes. This book extends coverage to those underserved and minority communities in the developed world. In a consistent chapter format, it discusses classification, pathophysiology, genomics, diagnosis, prevention and management of diabetes in economically challenged regions as well as underserved populations in affluent nations. Suggestions regarding future directions in the organization of diabetes care delivery, prevention and research priorities are also provided. The detailed identification of barriers to optimal care and the practical approach to the management and prevention of diabetes make Diabetes Mellitus in Developing Countries and Underserved Communities a valuable resource for clinicians, researchers and health policy leaders. Есть полнотекстовые версии (для доступа требуется авторизация)
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Форма документа : Однотомне видання
Шифр видання :
Назва : Research into Childhood-Onset Diabetes : From Study Design to Improved Management / . -1st ed. 2017.
Вихідні дані : Б.м.,Б.р.
Кільк.характеристики :VIII, 192 p. 12 illus., 8 illus. in color.
ISBN, Ціна 9783319402420: Б.ц.
Предметні рубрики: Diabetes.
Pediatrics.
Diabetes.
Pediatrics.
Зміст : Feeding the planet, energy for the future -- PART I: Up-To-Date in Childhood Type 1 Diabetes -- Diabetes ketoacidosis management in children and adolescents. ISPAD vs ISPED: similarities and differences -- Insulin and immune therapy in children and adolescents with type 1 diabetes -- Adolescent prevention of complications -- Hvidoere Study Group: What can be learned from observational studies -- Long term microvascular complications: new ideas for research -- Exercise in children with type 1 diabetes -- Nutritional aspects of type 1 diabetes: we need to keep struggling against paleontological dietetic regimens (how research helps us to do the right thing) -- Nutrition and insulin resistance during childhood and adolescence -- Diminished 1,25-dihydroxyvitamin D with preserved 25-hydroxyvitamin D levels in 10-18 year old youth with new-onset type 1 diabetes -- Risky beaviours in teens with type 1 diabetes: new ideas for research regarding a not too studied topic -- PART II: The technological route to the future -- Glucose sensors -- Glucose monitoring and insulin pump therapy in the management of children and adolescents with type 1 diabetes -- Advanced pump functions: bolus calculator, bolus types, temporary basal -- Regulatory aspects of new technology in diabetes: Can research help us?.
Анотація: This book offers a detailed update on research into diabetes with onset in childhood or adolescence. The coverage ranges from fundamental aspects such as study design and statistical analysis through to new ideas for research, the latest research findings, and implications of these findings for clinical care in childhood. Examples of topics addressed in this context include the prevention of diabetic complications, management of micro- and macrovascular complications, the roles of nutrition and exercise, insulin therapy, islet transplantation, and risky behaviors in teenagers. Attention is also focused on the latest technologies, including the artificial pancreas and continuous glucose monitoring, and associated regulatory aspects. The reader will find novel insights into the ways in which research is impacting on clinical management as well as advice on methodology and stimulating ideas on future research areas. The book is based on presentations delivered at the 15th ISPAD (International Society for Pediatric and Adolescent Diabetes) Research School for Physicians, held in Milan. It will be of interest for all diabetologists, pediatricians, dietitians, biomedical engineers, nurses, and students. Есть полнотекстовые версии (для доступа требуется авторизация)
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Форма документа : Однотомне видання
Шифр видання :
Назва : Bariatric and Metabolic Surgery : Indications, Complications and Revisional Procedures / . -1st ed. 2017.
Вихідні дані : Б.м.,Б.р.
Кільк.характеристики :XV, 206 p.
ISBN, Ціна 9788847039445: Б.ц.
Предметні рубрики: Surgery.
Metabolic diseases.
Diabetes.
Gastroenterology .
General Surgery.
Metabolic Diseases.
Diabetes.
Gastroenterology.
Зміст : 1 History of Obesity Surgery in Italy -- 2 Current indications to Bariatric Surgery in adult and children -- 3 Bariatric Surgery Worlwide -- 4 Evolution of Bariatric Surgery in Italy -- TECHNIQUES AND COMPLICATIONS – 5 Gastric Banding -- 6 Sleeve Gastrectomy -- 7 Gastric Bypass -- 8 One Anastomosis Gastric Bypass -- 9 Standard Bilio-Pancreatic-Diversion -- 10 Duodenal Switch -- 11 Single Anastomosis Duodeno-Ileal Bypass with Sleeve Gastrectomy -- 12 Ileal Interposition -- REVISIONAL SURGERY – 13 The problem of weight regain -- 14 Band Revision and Conversion to other procedures -- 15 Sleeve Revision and Conversion to other procedures -- 16 RYGB Revision and Conversion to other procedures -- SELECTED TOPICS – 17 The problem of GERD and Hiatal Hernia -- 18 Diabetes Surgery: current indications and techniques -- 19 Endoluminal Procedures -- 20 Other Bariatric Operations.
Анотація: This book describes the surgical bariatric procedures most frequently performed worldwide and examines their evolution in recent years both within Italy and internationally. For each operation, indications, the surgical technique, potential complications, and the outcomes with respect to weight and obesity-associated comorbidities are presented. In view of the significant failure rate revealed by studies on the long-term results of bariatric surgery, the problem of weight regain and revision surgery are also discussed in detail, covering the different types of revision, conversion to other procedures, and the main outcomes. In addition, individual chapters focus on selected topics of importance. The role of bariatric surgery in the cure of type 2 diabetes (“diabetes surgery”) is discussed and the debate over the significance of gastroesophageal reflux disease and hiatal hernia for choice of procedure is summarized. Finally, the most common endoluminal procedures, which have been gaining in importance, are described and other bariatric operations, outlined. Есть полнотекстовые версии (для доступа требуется авторизация)
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Форма документа : Однотомне видання
Шифр видання :
Автор(и) : Fisher Miles., McKay, Gerard.
Назва : Essentials of SGLT2 Inhibitors in Diabetes . -1st ed. 2017.
Вихідні дані : Б.м.,Б.р.
Кільк.характеристики :XI, 68 p. 13 illus. in color.
ISBN, Ціна 9783319432960: Б.ц.
Предметні рубрики: Diabetes.
Primary care (Medicine).
General practice (Medicine).
Endocrinology .
Diabetes.
Primary Care Medicine.
General Practice / Family Medicine.
Endocrinology.
Зміст : Overview of Type 2 Diabetes -- SGLT2 Inhibitors for Treating Diabetes -- Guidelines for the Treatment of Type 2 Diabetes Mellitus -- Using SGLT2 Inhibitors in Special Populations.
Анотація: Written by experts in the field, this clinical handbook explores the novel SGLT2 drug class for the treatment of diabetes. This book includes evidence-based guidelines, major clinical trials, and a discussion of treatment options currently available, as well as those currently in development. Essentials of SGLT2 Inhibitors is an ideal educational resource for busy medical professionals who need to stay up-to-date with diabetes treatment advances in order to provide the best possible clinical care for their patients. Есть полнотекстовые версии (для доступа требуется авторизация)
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Форма документа : Однотомне видання
Шифр видання :
Назва : Bedside Approach to Autonomic Disorders : A Clinical Tutor / . -1st ed. 2017.
Вихідні дані : Б.м.,Б.р.
Кільк.характеристики :V, 143 p. 22 illus., 10 illus. in color.
ISBN, Ціна 9783319051437: Б.ц.
Предметні рубрики: Neurology .
Cardiology.
Diabetes.
Urology.
Neurology.
Cardiology.
Diabetes.
Urology.
Зміст : General Approach: an introduction to autonomic physiology and pathophysiology -- Autonomic History Taking and Key Symptoms -- Autonomic Examination and Management of Cardiovascular Autonomic Dysfunction and Disease -- Autonomic Examination and Management of Sweating Disorders -- Autonomic Examination and Management of Bladder and Sexual Dysfunction -- Autonomic Examination and Management of Gastrointestinal Dysfunction -- Autonomic Examination and Management of Hyperactivity Syndromes -- Autonomic Examination and Management of Sleep: Cardiovascular and Ventilatory Disorders.
Анотація: This book is a guide to the everyday clinical management of disorders of the autonomic nervous system, from identification of the key symptoms of autonomic involvement and comprehensive history taking to choice of treatment. The book will assist the reader in determining the anatomic distribution of the disease, as well as underlying autonomic syndromes, and in transforming the clinical picture into a coherent explanation of the patient’s autonomic problem. In addition, guidelines are provided on selection of the most appropriate autonomic and laboratory tests and formulation of appropriate non-pharmacological and pharmacological management strategies. With cases drawn from clinical experience and a list of available online resources, Bedside Approach to Autonomic Disorders will aid the reader in acquiring the skills that are mandatory in order to put patients on the right clinical track. It will be a valuable guide for trainees and young doctors interested in autonomic disorders from the fields of neurology, internal medicine, cardiology, diabetology, and urology. Есть полнотекстовые версии (для доступа требуется авторизация)
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Форма документа : Однотомне видання
Шифр видання :
Назва : Integrated Diabetes Care : A Multidisciplinary Approach / . -1st ed. 2017.
Вихідні дані : Б.м.,Б.р.
Кільк.характеристики :XIII, 250 p. 71 illus., 57 illus. in color.
ISBN, Ціна 9783319133898: Б.ц.
Предметні рубрики: Diabetes.
Metabolic diseases.
Endocrinology .
Diabetes.
Metabolic Diseases.
Endocrinology.
Зміст : 1. An Introduction to Integrated Care and Diabetes Integrated Care -- 2. Integrating Outpatient Care the Toyota Way: An Individualized Multidisciplinary Team-Care Model for Diabetes Care Delivery -- 3. Approaches to Integrated Diabetes Care: United States: San Francisco -- 4. A Primary Healthcare System Approach to Improving Quality of Care and Outcomes in People with Diabetes: The University of Pittsburgh Medical Center Experience -- 5. Integrated Diabetes Care in Hong Kong: From Research to Practice to Policy -- 6. Approaches to Integrated Diabetes Care: A South African Approach -- 7. English Approaches to Integrated Diabetes Care: The East Cambridgeshire and Fenland Diabetes Integrated Care Initiative: A Multiple Provider Approach -- 8. UK Approaches to Integrated Diabetes Care: Derby—A Joint Venture Model Under the NHS -- 9. Integrated Diabetes Care: Coventry and Warwickshire Approach -- 10. Integrated Diabetes Care in Germany: Triple Aim in Gesundes Kinzigtal -- 11. Approaches to Integrated Diabetes Care in the Netherlands -- 12. Integrated Diabetes Care in Sweden -- 13. Integrated Diabetes Care for Adults with Diabetes: A Patient Organisation Perspective -- 14. Training for Diabetes Integrated Care: A Diabetes Specialist Physician Perspective from the English NHS -- 15. Diabetes Integrated Care: Are We There Yet?.
Анотація: This book collates evidence of worldwide approaches to both horizontal integration (across disciplines) and vertical integration (across organizations) in diabetes care and describe what was done, what worked and what appeared to be the barriers to achieving the goals of the programmes. Evidence is sought from groups who have developed different approaches to integrating diabetes care in different health systems (such as insurance vs taxpayer funded, single vs multiple organization, published vs unpublished). A final chapter brings the evidence together for a final discussion about what seems to work and what does not. Integrated Diabetes Care - A Multidisciplinary Approach showcases innovative approaches to diabetes, showing the reader new ways by which problems are addressed and their putative outcomes. Есть полнотекстовые версии (для доступа требуется авторизация)
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Форма документа : Однотомне видання
Шифр видання :
Автор(и) : Stewart Michael W.
Назва : Diabetic Retinopathy : Current Pharmacologic Treatment and Emerging Strategies / . -1st ed. 2017.
Вихідні дані : Б.м.,Б.р.
Кільк.характеристики :XIII, 268 p. 61 illus., 48 illus. in color.
ISBN, Ціна 9789811035098: Б.ц.
Предметні рубрики: Diabetes.
Ophthalmology.
Diabetes.
Ophthalmology.
Зміст : 1. Diabetes and Diabetic Retinopathy: Overview Of A World-Wide Epidemic -- 2. The Diabetic Retina: Anatomy and Pathophysiology -- 3. Treatment of Diabetic Retinopathy: A Historical Perspective -- 4. Targeting Vascular Endothelial Growth Factor -- 5. Corticosteroids: Targeting Multiple Cytokines and Chemokines -- 6. Current Treatment Recommendations -- 7. Vitreolysis: Targeting the Vitreoretinal Interface -- 8. Investigational Medications -- 9. Safety Considerations of Pharmacotherapy -- 10. Socioeconomic Cost of Diabetic Retinopathy and Therapy.
Анотація: A well-illustrated and comprehensive analysis of the treatment of diabetic retinopathy, this book covers current treatment options and guidelines, whilst also providing a detailed discussion of emerging therapeutic targets. Existing therapeutic options are covered in depth, with a major focus on anti-vascular endothelial growth factor drugs and sustained release corticosteroids, including a review of trial results supporting current treatment guidelines. The use of agents off-label is also discussed. Controversial topics are discussed in detail with an emphasis on helping the reader make informed decisions, particularly when treating patients for which several treatment approaches may be appropriate because trial data does not clearly define the best option. Emerging therapeutic areas are evaluated, as work continues to identify agents that produce superior morphologic responses and visual acuity gains by targeting other molecules that contribute to diabetic retinopathy. Promising new drugs, targets and delivery systems are identified, and their development analysed. Есть полнотекстовые версии (для доступа требуется авторизация)
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Форма документа : Однотомне видання
Шифр видання :
Назва : Hormones, Metabolism and the Benefits of Exercise . -1st ed. 2017.
Вихідні дані : Б.м.,Б.р.
Кільк.характеристики :X, 102 p.
ISBN, Ціна 9783319727905: Б.ц.
Предметні рубрики: Molecular biology.
Health promotion.
Endocrinology .
Cardiology.
Diabetes.
Metabolic diseases.
Molecular Medicine.
Health Promotion and Disease Prevention.
Endocrinology.
Cardiology.
Diabetes.
Metabolic Diseases.
Зміст : Introduction -- Human brown adipose tissue plasticity: hormonal and environmental manipulation -- The energy sensor AMPK: Adaptations to exercise, nutritional and hormonal signals -- Plasma steroids and cardiorespiratory fitness response to regular exercise -- Sending the signal: Muscle glycogen availability as a regulator of training adaptation -- Optimized engagement of macrophages and satellite cells in the repair and regeneration of exercised muscle -- Skeletal muscle microRNAs: Roles in differentiation, disease and exercise -- Tryptophan-kynurenine metabolites in exercise and mental health -- FNDC5/irisin - their role in the nervous system and as a mediator for beneficial effects of exercise on the brain.
Анотація: The world is faced with an epidemic of metabolic diseases such as obesity and type 2 diabetes. This is due to changes in dietary habits and the decrease in physical activity. Exercise is usually part of the prescription, the first line of defense, to prevent or treat metabolic disorders. However, we are still learning how and why exercise provides metabolic benefits in human health. This open access volume focuses on the cellular and molecular pathways that link exercise, muscle biology, hormones and metabolism. This will include novel “myokines” that might act as new therapeutic agents in the future. Есть полнотекстовые версии (для доступа требуется авторизация)
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10.

Форма документа : Однотомне видання
Шифр видання :
Назва : Managing Gastrointestinal Complications of Diabetes . -1st ed. 2017.
Вихідні дані : Б.м.,Б.р.
Кільк.характеристики :VII, 130 p. 6 illus. in color.
ISBN, Ціна 9783319486628: Б.ц.
Предметні рубрики: Diabetes.
Gastroenterology .
General practice (Medicine).
Primary care (Medicine).
Endocrinology .
Diabetes.
Gastroenterology.
General Practice / Family Medicine.
Primary Care Medicine.
Endocrinology.
Зміст : Chapter 1 Introduction -- Chapter 2 Esophageal disease in diabetes mellitus -- Chapter 3 -- Diabetic gastroparesis -- Chapter 4 -- Small intestine and colon complications patients with diabetes -- Chapter 5 Non-alcoholic fatty liver disease -- Chapter 6 -- Non-alcoholic fatty liver disease and hepatocellular carcinoma -- Chapter 7 Diabetes, specific heptobiliary disease, and treatment -- Chapter 8 Diabetes, cirrhosis, and liver transplantation -- Chapter 9 Diabetes and the exocrine pancreas.
Анотація: An ideal clinical handbook for medical professionals that regularly treat patients with diabetes and comorbid gastrointestinal complications. The concise format provides evidence-based content with a targeted emphasis on diagnosis, as up to 75% of patients visiting diabetes clinics report significant gastrointestinal symptoms. Includes guidelines for complication prevention, treatment, and long-term disease management. Есть полнотекстовые версии (для доступа требуется авторизация)
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11.

Форма документа : Однотомне видання
Шифр видання :
Назва : Free Fatty Acid Receptors . -1st ed. 2017.
Вихідні дані : Б.м.,Б.р.
Кільк.характеристики :VIII, 256 p. 70 illus.
ISBN, Ціна 9783319506937: Б.ц.
Предметні рубрики: Pharmacology.
Human physiology.
Diabetes.
Systems biology.
Medical biochemistry.
Pharmacology/Toxicology.
Human Physiology.
Diabetes.
Systems Biology.
Medical Biochemistry.
Зміст : Ligands at Free Fatty Acid Receptor 1 (GPR40) -- Ligands at Free Fatty Acid Receptor 2/3 (GPR43)/GPR41 -- Ligands at GPR84 -- Ligands at Free Fatty Acid Receptor 4 (GPR120) -- Homology modelling of FFA receptors -- Sensors for FFA receptors -- Key questions for translation of FFA receptors from pharmacology to medicines -- Polymorphic variation in FFA receptors. Functions and consequences -- The role and future of FFA1 as a therapeutic target -- Gut hormone regulation and secretion via FFA1 and FFA4 -- The role of FFA2 and FFA3 in metabolic regulation -- Anti-inflammatory and insulin sensitizing effects of free fatty acid receptors -- Free Fatty Acid receptors and cancer. .
Анотація: This book highlights the important role free fatty acids (FFA) play as potential drug targets. While FFA have long been considered byproducts of cell metabolism, they are now recognized as ligands that regulate cell and tissue function via G-protein-coupled receptors. At least three receptors have been identified for which FFA appear to be the endogenous ligands. Есть полнотекстовые версии (для доступа требуется авторизация)
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12.

Форма документа : Однотомне видання
Шифр видання :
Назва : Principles of Diabetes Mellitus . -3rd ed. 2017.
Вихідні дані : Б.м.,Б.р.
Кільк.характеристики :197 illus., 101 illus. in color. eReference.
ISBN, Ціна 9783319187419: Б.ц.
Предметні рубрики: Diabetes.
Endocrinology .
Primary care (Medicine).
Diabetes.
Endocrinology.
Primary Care Medicine.
Зміст : Part I: The Main Events in the History of Diabetes Mellitus -- Part II: Physiology of Glucose Metabolism -- Part III: Diagnosis and Epidemiology of Diabetes -- Part IV: Genes and Diabetes -- Part V: Diabetes Syndromes -- Part VI: Complications of Diabetes -- Part VII: Related Disorders -- Part VIII: Therapy of Diabetes Mellitus – General Principles -- Part IX: Diabetes Prevention -- Part X -- Resources for Patients with Diabetes.
Анотація: The third edition of this important work is a timely update to the comprehensive textbook first published in 2002 and reissued in a second edition in 2010. The past few years have witnessed major developments in our understanding of diabetes and in therapeutic approaches to this disease and its numerous complications. Thus, all chapters have been significantly revised and updated with current evidence and best practices, and four brand new chapters are included, discussing the potential role of vitamin D in the pathogenesis of diabetes, peculiarities of diabetes in the elderly, oral manifestations of diabetes, and the current state of bariatric surgery. Written by an international group of experts and carefully edited by a leading authority on the subject, Principles of Diabetes Mellitus, Third Edition is an invaluable resource for researchers and physicians of all specialties, as well as medical students and investigators of all aspects of diabetes, who deal with an illness that has reached epidemic proportions. Есть полнотекстовые версии (для доступа требуется авторизация)
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13.

Форма документа : Однотомне видання
Шифр видання :
Назва : Mechanisms of Vascular Defects in Diabetes Mellitus . -1st ed. 2017.
Вихідні дані : Б.м.,Б.р.
Кільк.характеристики :XVIII, 579 p. 75 illus., 54 illus. in color.
ISBN, Ціна 9783319603247: Б.ц.
Предметні рубрики: Cell biology.
Diabetes.
Cell Biology.
Diabetes.
Зміст : Section 1 Introduction -- The Global Burden Of Diabetes And Its Vascular Complications -- SECTION 2 Pathogenesis -- Genetic Basis For Increased Risk For Vascular Diseases In Diabetes -- Vascular Remodelling In Diabetes Mellitus -- Pathogenesis Of The Plaque Vulnerability In Diabetes Mellitus -- Endothelial Dysfunction In Diabetes -- Smooth Muscle Cells In Diabetes Mellitus -- Monocytes Factors In Pathogenesis Of Vascular Lesions In Diabetes -- Endothelial Progenitor Cell Dysfunction In The Pathogenesis Of Vascular Complications Of Diabetes -- Pathogenetic mechanisms in diabetic retinopathy: from molecules to cells to tissues -- Perspectives on the vascular pathogenesis of diabetic neuropathy -- SECTION 3 Molecular mechanisms -- The Renin - Angiotensin System And Diabetes -- Adipokines And Vascular Disease In Diabetes -- G-Proteins In Vascular Complications Of Diabetes -- Histone Deacetylases In Vascular Pathophysiology: Regulation By Vasoactive Peptides And Growth Factors -- Role of non-coding RNAs in vascular complications of diabetes mellitus -- SECTION 4 Hemostatic Factors -- Diabetes As A Prothrombotic State -- Mechanisms Of Hypercoagulation And Aberrant Clot Lyses In Type 2 Diabetes -- Platelet Dysfunction In Type-2 Diabetes Mellitus -- SECTION 5 Metabolic Factors -- Advanced Glycation End Products In Diabetic Complications -- Atherogenicdyslipoproteinemia In Type 2 Diabetes Mellitus -- Vascular Remodeling: Homocysteine And Diabetes -- SECTION 6 Pharmacological Therapies -- Mechanisms Of Action Of Drugs For Treating Endothelial Dysfunction In Diabetes Mellitus -- Beneficial Effects Of Inorganic Nitrate/Nitrite On Vascular Function And Blood Pressure In Diabetes -- Myeloperoxidase (MPO): Do We Need Inhibitors?.
Анотація: This book comprising 24 chapters is devoted to the mechanisms for the pathogenesis of the spectrum of vascular diseases in diabetes. Cellular events and molecular pathways that regulate the structure and function of both small and large arteries, the dysregulation in these vessels caused by hyperglycemia, oxidative stress, metabolic and haemostatic derangements secondary to diabetes, are discussed. Mechanisms of vascular remodelling and rupture of atherosclerotic plaques in diabetes are also covered. Several of the reviews also discuss therapeutic targets and drugs employed to reduce endothelial dysfunction and vascular inflammation in diabetes. All articles are authored by experts in their respective research fields. This compendium will be of interest to both basic scientists and clinicians in the pursuit of unravelling the molecular basis of vascular diseases and also to those who seek to identify targets for therapy of vascular complications of diabetes. Есть полнотекстовые версии (для доступа требуется авторизация)
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