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Електронний каталог бібліотеки ЗДМФУ (237)

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Форма документа : Однотомне видання
Шифр видання :
Автор(и) : Bikfalvi Andreas.
Назва : A Brief History of Blood and Lymphatic Vessels . -1st ed. 2017.
Вихідні дані : Б.м.,Б.р.
Кільк.характеристики :XIII, 192 p. 61 illus., 52 illus. in color.
ISBN, Ціна 9783319743769: Б.ц.
Предметні рубрики: Human physiology.
Medicine—History.
Biology—History.
Cardiology.
Philosophy and science.
Human Physiology.
History of Medicine.
History of Biology.
Cardiology.
Philosophy of Science.
Зміст : The vasculature, what is it? -- Historical consideration -- The vasculature in evolution -- Where it all began -- Culture of vascular cells in vitro -- The discovery of the first stimulating factors of blood vessels -- Vascular Endothelial growth factor (VEGF) : the cornerstone of angiogenesis stimulators -- Inhibition of angiogenesis "successes and deceptions" -- Stimulating angiogenesis -- The story is more complicated than anticipated -- How to study angiogenesis -- Lymphangiogenesis joins in -- Endothelial progenitors and stem cells -- The neuronal connection -- Vascular targeting and vessel destruction ("Vascular targeting") -- What future for angiogenesis? -- Philosophical aspect of the vascular tree -- Concluding remarks.
Анотація: This book provides a comprehensive account of vascular biology and pathology and its significance for health and disease. It systematically and chronologically explains how we came to our current understanding of the vasculature and it´s function today, and describes in an entertaining way the diverse flaws and turns in science and medicine from the past. It thereby offers a complete and well-studied history on vascular biology and medicine. The book has an easy-to-read style and is written for students as well as scientists, physicians and lecturers in the field of biomedicine, human physiology, cardiology and hematology. Есть полнотекстовые версии (для доступа требуется авторизация)
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Форма документа : Однотомне видання
Шифр видання :
Назва : Cancer Therapeutic Targets . -1st ed. 2017.
Вихідні дані : Б.м.,Б.р.
Кільк.характеристики :51 illus., 42 illus. in color. eReference.
ISBN, Ціна 9781441907172: Б.ц.
Предметні рубрики: Cancer research.
Oncology .
Laboratory medicine.
Internal medicine.
Molecular biology.
Pharmacology.
Cancer Research.
Oncology.
Laboratory Medicine.
Internal Medicine.
Molecular Medicine.
Pharmacology/Toxicology.
Зміст : AKT -- Anti-4-1BB/4-1BBL -- Anti-B7-H4 -- Anti-CD40/Anti CD40L -- Anti-Idiotype antibodies -- Anti-Programmed Death 1 (PD1) -- B7.1 -- Bacterial Vaccines -- Brachyury -- CCL21 -- CD4+ T Cells -- CD8 T Cells -- CEA -- CTLA-4 -- Dendritic cells -- DNA Vaccines -- EGFR, Immunology -- Fc Gamma R -- Gangliosides -- Glucocorticoid-Induced TNF Receptor (GITR) -- GM-CSF and Whole Cells -- gp100 -- HER2/neu -- indoleamine 2,3-dioxygenase -- Integrins, Immunology -- Interferon alpha -- Interleukin 2 -- Interleukin 7 -- Interleukin 12 -- Interleukin 15 -- Interleukin 21 -- Lymphocyte Activation Gene 3 (LAG-3) -- MART-1 -- MUC1 -- NK Cells -- P53, Immunology -- PAP -- Peptide Vaccine: Overview -- Proteins (Mesothelin) -- PSA -- Survivin -- Telomerase-related proteins -- TGF Beta Receptors -- TLR7 and TLR8, Resiquimod, and 852A -- TLR9 -- Transforming Growth Factor β -- Tregs -- Tyrosinase: Overview -- VEGF -- Viral-Like Proteins -- Whole-Cell Vaccines -- FGF-FGFR Signaling in Cancer -- MMPs -- PDGF -- TIE -- VEGF A -- VEGF Ligands -- AXL -- B-Raf -- CKIT -- DNA Repair, Overview -- EGFR, Growth factors -- HER3 -- IGF 1 and IGF 2 -- Jak2/Stat5a/b Pathway in Prostate Cancer -- JNK Signaling in Diseases -- K-Ras -- MET -- NEDD9 -- N-Ras -- P38 -- Rac 1 -- Type I Insulin-Like Growth Factor Receptor -- Anti-apoptotic Bcl-2 -- BH3-Only Mimetics -- Caspase -- DR4 and DR5 -- FLIP -- MLH1 -- NF-κB -- PARP -- ROS -- X-Linked IAP -- APC -- AR, Overview -- BRCA 1 and 2 -- Cell Cycle Related Kinases -- ER -- Histone Deacetylases (HDAC) -- Methylation -- PR -- Retinoids -- Topoisomerase 1 -- Topoisomerase 2 -- VDR.
Анотація: In the past decade, we have experienced an explosion of new information about cancer therapeutic targets. Many of the targets have been validated by the discovery and approval of new medicines which have been approved for the treatment of cancer. On the heels of these successes, innumerable new targets and new potential therapeutics are being developed by many different groups including government agencies, pharmaceutical companies, biotechnology companies, academic institutions, and individual investigators. Understanding the expanding "universe" of cancer therapies is therefore becoming impossible and no single source exists which serves as a reference for the involved parties. Further, the interested parties have vastly different areas of expertise, from focused laboratory based science, to clinical research, to corporate and regulatory oversight. The text would be updated every two years, more often depending on pace of change, interest and sales. While useful online, this reference book would likely be kept in hard copy as well. Есть полнотекстовые версии (для доступа требуется авторизация)
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Форма документа : Однотомне видання
Шифр видання :
Назва : The Neuropilins: Role and Function in Health and Disease . -1st ed. 2017.
Вихідні дані : Б.м.,Б.р.
Кільк.характеристики :VI, 239 p. 38 illus., 28 illus. in color.
ISBN, Ціна 9783319488240: Б.ц.
Предметні рубрики: Immunology.
Molecular biology.
Cancer research.
Neurosciences.
Developmental biology.
Cell biology.
Immunology.
Molecular Medicine.
Cancer Research.
Neurosciences.
Developmental Biology.
Cell Biology.
Зміст : Molecular mechanisms of neuropilin mediated VEGF and other growth factors induced signal transduction -- 1. The role of the neuropilins in VEGF signal transduction -- 2. The role of neuropilins in signaling induced by non-VEGF growth factors -- 3. Structure function studies of neuropilins in the context of their interaction with VEGF and VEGF receptors. Semaphorin signaling -- 1. Stucture function studies of functional class-3 semaphorin receptors -- 2. Control of cytoskeletal organization by class-3 semaphorins -- 3. Control of cell adhesion by class-3 semaphorin activated signaling -- Short Topics. 4. Gating of plexin-D1 function by neuropilin -- 5. Interaction of neuropilins with cell adhesion receptors and its effect on class-3 semaphorin signaling. Neuropilins as a regulators of developmental angiogenesis and lymphangiogenesis -- 1. Role of neuropilins in the regulation of developmental angiogenesis -- 2. The role of the neuropilins in the development of the lymphatic system -- Short Topics -- 3. The role of the neuropilins in the determination of artery/vein identity -- 4. Neuropilin-1 mediated differentiation of multipotent progenitor cells to endothelial cells -- 5. Role of neuropilin-1 and Phactr-1 in tube formation. Neuropilins as regulators of immune responses 1. Immunological functions of the neuropilins -- Short Topics. 2. Stability and function of regulatory T cells is maintained by a neuropilin-1- semaphorin-4a axis -- 3. Neuropilin 1 guides regulatory T cells into VEGF-producing melanomas. The role of neuropilins in tumor progression 1. Neuropilins as regulators of tumor progression -- Short Topics. 2. Neuropilin-1 on cancer stem cells -- 3. Sema3A induced neuropilin-1 mediated recruitment of endothelial progenitor cells to tumors -- 4. Neuropilins mediate recruitment of macrophages to hypoxic regions in tumors. Nervous system. 1. The role of neuropilins and their semaphorin and VEGF ligands in the development and function of the nervous system -- Short Topics. 2. Neuropilins and neurotrophins in central nervous system development -- The role of neuropilins in retinal development and retinal diseases. 1. The role of the neuropilins in the development of the retina and retinal diseases.-.
Анотація: This book covers basic research topics such as the structure-function relationships of neuropilins and mechanisms of neuropilin-mediated signal transduction, details the most important roles of the neuropilins in developmental biology, and addresses their roles in various conditions such as cancer and various eye diseases. The two neuropilin genes encode scaffold receptors that can bind several different ligands, and also associate with many other receptors and modify their activity. Further, it has been confirmed that they play important roles in the shaping of major organs and tissues such as the nervous system and the vascular system, and that they can modulate immune responses. The book offers a helpful guide for biomedical researchers and all scientists active in the neurosciences, vascular and molecular biology, as well as developmental biology and immunology. Есть полнотекстовые версии (для доступа требуется авторизация)
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Форма документа : Однотомне видання
Шифр видання :
Назва : Therapeutic Angiogenesis . -1st ed. 2017.
Вихідні дані : Б.м.,Б.р.
Кільк.характеристики :VI, 266 p. 57 illus., 37 illus. in color.
ISBN, Ціна 9789811027444: Б.ц.
Предметні рубрики: Cardiology.
Regenerative medicine.
Tissue engineering.
Cardiology.
Regenerative Medicine/Tissue Engineering.
Зміст : Chapter 1: Introduction Section: Over View of Therapeutic Angiogenesis -- Part I : Cell Therapy -- Chapter 2: Autologous Bone Marrow Mononuclear Cell Implantation in Extremities with Critical Limb Ischemia -- Chapter 3: Peripheral Blood Mononuclear Cells for Limb Ischemia -- Chapter 4: Endothelial Progenitor Cells for Ischemic Diseases -- Chapter 5: Therapeutic Angiogenesis With Adipose Tissue-derived Regenerative Cells -- Chapter 6: Cell Therapy for Ischemic Heart Disease -- Chapter 7: Angiogenic Therapy for Ischemic Cardiomyopathy with Cell Sheet Technology -- Part II: Gene Therapy -- Chapter 8: The Role of VEGF in Extremities -- Chapter 9: HGF Gene Therapy for Therapeutic Angiogenesis in Peripheral Artery Disease -- Chapter 10: Fibroblast Growth Factor in Extremities -- Part III: Other Therapy -- Chapter 11: Low-intensity Pulsed Ultrasound -- Chapter 12: Low-energy Extracorporeal Shock Wave Therapy -- Chapter 13: Granulocyte-Colony Stimulating Factor -- Chapter 14: Waon Therapy: Effect of Thermal Stimuli on Angiogenesis -- Chapter 15: Exercise -- Chapter 16: Nanoparticle-mediated Endothelial Cell-selective Drug Delivery System.
Анотація: The book discusses recent findings and current perspectives on therapeutic angiogenesis. Studies have shown that therapies such as cell implantation and transfer of gene encoding for angiogenic growth factors are effective in improving symptoms in patients with critical limb ischemia, who previously had no treatment option other than amputation. The book discusses these therapies and presents data collected in clinical studies over the past decade. Despite significant advances in therapeutic angiogenesis since the first clinical studies in the early 21st century, it has been largely ignored in the literature. This comprehensive book fills that gap, making it a valuable resource for both researchers and practitioners alike. Есть полнотекстовые версии (для доступа требуется авторизация)
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Статистика за 28.07.2024
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